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Jocelyn A Holash

from Yonkers, NY
Age ~57
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Also known as:
Jocelyn Ann Holash, Jocelyn Te Holash, Jocelyn A Doyle, Joclyn Holash
Related to:
Joan M Doyle, 98Charles M Doyle, 65Edward P Doyle, 93
Connected to:
Chad M Holash, 40Elaine Holata, 67Kimberlee R Holata, 50Peter C Holaves, 54Abigail A Holaway, 29Kimberlee A Holaway, 72Louis R Holaway, 67Merna M Holaway, 101Tsuyako Holaway, 98Makenzie L Holb, 32

Jocelyn Holash Phones & Addresses

  • Yonkers, NY
  • Stateline, NV
  • 321 Channing Way, Alameda, CA 94502 (510) 521-7903
  • Pelham, NY
  • San Diego, CA
  • 321 Channing Way, Alameda, CA 94502

Work

Position: Professional/Technical

Education

Degree: Graduate or professional degree

Publications

Us Patents

Method Of Tumor Regression With Vegf Inhibitors

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US Patent:
7354578, Apr 8, 2008
Filed:
Jun 4, 2004
Appl. No.:
10/860958
Inventors:
Jessica Kandel - New York NY, US
Jocelyn Holash - Alameda CA, US
Darrell Yamashiro - Westwood NJ, US
Jianzhong Huang - New York NY, US
George Yancopoulos - Yorktown Heights NY, US
John Rudge - Mahopac NY, US
Assignee:
Regeneron Pharmaceuticals, Inc. - Tarrytown NY
International Classification:
A61K 38/18
C07K 14/71
C12N 15/62
US Classification:
4241341, 4241921, 514 2, 514 12, 530350, 536 234
Abstract:
Methods of regressing or inhibiting a tumor in a subject by administering an agent capable of blocking, inhibiting, or ameliorating vascular endothelial growth factor (VEGF)-mediated activity to a subject in need thereof such that the tumor is regressed or inhibited. The method of the invention results in a reduction of tumor size and inhibition of tumor metastases. This method is particularly useful for patients suffering from bulky, metastatic cancers.

Therapeutic Combination Of A Vegf Antagonist And Anti-Hypertensive Agent

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US Patent:
7354581, Apr 8, 2008
Filed:
Feb 8, 2006
Appl. No.:
11/350145
Inventors:
Jesse M. Cedarbaum - Larchmont NY, US
Jocelyn Holash - Alameda CA, US
Assignee:
Regeneron Pharmaceuticals, Inc. - Tarrytown NY
International Classification:
A61K 38/18
C07K 14/71
C12N 15/62
US Classification:
4241341, 4241921, 514 2, 514 12, 530350, 536 234
Abstract:
Disclosed are compositions and methods for treating a disease or condition related to angiogenesis with a vascular endothelial growth factor (VEGF) inhibitor and one or more anti-hypertensive agent(s). The method of the invention is useful for preventing the development of hypertension and/or reducing hypertension in a subject treated with a VEGF inhibitor.

Use Of Vegf Antagonists For The Treatment Of Malignant Gliomas

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US Patent:
7354582, Apr 8, 2008
Filed:
Mar 10, 2006
Appl. No.:
11/373462
Inventors:
W. K. Alfred Yung - Houston TX, US
Juan Fueyo - Houston TX, US
Jesse M. Cedarbaum - Larchmont NY, US
Jocelyn Holash - Alameda CA, US
Assignee:
Regeneron Pharmaceuticals, Inc. - Tarrytown NY
International Classification:
A61K 38/18
C07K 14/71
C12N 15/62
US Classification:
4241341, 4241921, 514 2, 514 12, 530350, 536 234
Abstract:
Methods for treating a human patient suffering from a brain tumor, including glioblastoma, by administering an effective amount of a vascular endothelial growth factor (VEGF) inhibitor to the human patient. The VEGF inhibitor is a VEGF antagonist protein comprising a dimeric protein having two fusion polypeptides having the sequence of SEQ ID NO:2.

Therapeutic Combination Of A Vegf Antagonist And Anti-Hypertensive Agent

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US Patent:
7449182, Nov 11, 2008
Filed:
Dec 14, 2007
Appl. No.:
12/002115
Inventors:
Jesse M. Cedarbaum - Larchmont NY, US
Jocelyn Holash - Alameda CA, US
Assignee:
Regeneron Pharmaceuticals, Inc. - Tarrytown NY
International Classification:
A61K 38/18
C07K 14/71
C12N 15/62
US Classification:
4241341, 4241921, 514 2, 514 12, 530350, 536 234
Abstract:
Disclosed are compositions and methods for treating a disease or condition related to angiogenesis with a vascular endothelial growth factor (VEGF) inhibitor and one or more anti-hypertensive agent(s). The method of the invention is useful for preventing the development of hypertension and/or reducing hypertension in a subject treated with a VEGF inhibitor.

Antitumor Combinations Containing A Vegf-Inhibiting Agent And 5Fu Or A Derivative Thereof

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US Patent:
8388963, Mar 5, 2013
Filed:
Jul 24, 2009
Appl. No.:
12/508834
Inventors:
Patricia Vrignaud - Combs la Ville, FR
Marielle Chiron-Blondel - Paris, FR
Marie-Christine Bissery - Charenton le Pont, FR
Eric Furfine - Croton on Hudson NY, US
Jocelyn Holash - Yonkers NY, US
Jesse M. Cedarbaum - Larchmont NY, US
Assignee:
Aventis Pharma SA - Antony
Regeneron Pharmaceuticals Inc - Tarrytown NY
International Classification:
A61K 38/18
C07K 14/71
C12N 15/62
US Classification:
4241341, 4241921, 514 11, 514 193, 514 212, 530350
Abstract:
This invention relates to antitumor combinations comprising a VEGF inhibitor combined with 5-fluorouracil or with a 5-fluoropyrimidine derivative that are therapeutically useful in the treatment of neoplastic diseases, and pharmaceutical compositions comprising such combinations.

Use Of A Vegf Antagonist In Combination With Radiation Therapy

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US Patent:
20050112061, May 26, 2005
Filed:
Jul 30, 2004
Appl. No.:
10/909011
Inventors:
Jocelyn Holash - Alameda CA, US
George Yancopoulos - Yorktown Heights NY, US
Phyllis Wachsberger - Berwyn PA, US
Adam Dicker - Cherry Hill NJ, US
Randy Burd - Wayne PA, US
International Classification:
A61K051/00
A61K039/395
A61K038/17
US Classification:
424001490, 424145100, 514012000
Abstract:
Methods of treating cancer and/or reducing or inhibiting tumor growth in a subject in need thereof, comprising administering pharmaceutical composition comprising a vascular endothelial cell growth factor (VEGF) trap, in combination with radiation therapy and/or a therapeutic radiopharmaceutical.

Use Of A Vegf Antagonist In Combination With Radiation Therapy

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US Patent:
20050196340, Sep 8, 2005
Filed:
Nov 29, 2004
Appl. No.:
10/998881
Inventors:
Jocelyn Holash - Alameda CA, US
George Yancopoulos - Yorktown Heights NY, US
Phyllis Wachsberger - Berwyn PA, US
Adam Dicker - Cherry Hill NJ, US
Randy Burd - Wayne PA, US
International Classification:
A61K038/17
A61K051/00
US Classification:
424001690, 514012000
Abstract:
Methods of treating cancer and/or reducing or inhibiting tumor growth in a subject in need thereof, comprising administering pharmaceutical composition comprising a vascular endothelial cell growth factor (VEGF) antagonist, in combination with radiation therapy and/or a therapeutic radiopharmaceutical.

Antitumor Combinations Containing A Vegf-Inhibiting Agent And 5Fu Or A Derivative Thereof

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US Patent:
20060178305, Aug 10, 2006
Filed:
Dec 2, 2005
Appl. No.:
11/293761
Inventors:
Patricia Vrignaud - Combs La Ville, FR
Marielle Chiron-Blondel - Paris, FR
Marie-Christine Bissery - Vitry Sure Seine, FR
Eric Furfine - Croton on Hudson NY, US
Jocelyn Holash - Alameda CA, US
Jesse Cedarbaum - Larchmont NY, US
Assignee:
Aventis Pharma S.A. - Antony
International Classification:
A61K 38/17
A61K 31/7072
A61K 31/513
A61K 31/525
US Classification:
514012000, 514049000, 514269000, 514251000
Abstract:
This invention relates to antitumor combinations comprising a VEGF inhibitor combined with 5-fluorouracil or with a 5-fluoropyrimidine derivative that are therapeutically useful in the treatment of neoplastic diseases, and pharmaceutical compositions comprising such combinations.
Control profile
Jocelyn A Holash from Yonkers, NY, age ~57 Get Report