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Sokol A Haxhinasto

from Brookfield, CT
Age ~48

Sokol Haxhinasto Phones & Addresses

  • 4 Kellie Ln, Brookfield, CT 06804 (203) 775-5712
  • 1768 Beacon St, Brookline, MA 02445 (617) 738-4326
  • Danbury, CT
  • Quincy, MA
  • 800 Benton St, Iowa City, IA 52246 (319) 688-9541
  • Boston, MA
  • Burlington, IA
  • 800 W Benton St APT 216A, Iowa City, IA 52246 (319) 573-8044

Work

Position: Machine Operators, Assemblers, and Inspectors Occupations

Education

Degree: Bachelor's degree or higher

Publications

Us Patents

Anti-Msr1 Antibodies And Methods Of Use Thereof

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US Patent:
20230079407, Mar 16, 2023
Filed:
Apr 22, 2022
Appl. No.:
17/727432
Inventors:
- Tarrytown NY, US
Viktoria GUSAROVA - Pleasantville NY, US
Amy HAN - Hockessin DE, US
Sokol HAXHINASTO - Brookfield CT, US
Christos KYRATSOUS - Irvington NY, US
Andrew J. MURPHY - Croton-on Hudson NY, US
Thomas NITTOLI - Pearl River NY, US
William OLSON - Yorktown Heights NY, US
Matthew SLEEMAN - White Plains NY, US
Anna ZUMSTEG - Elmsford NY, US
International Classification:
C07K 16/28
A61K 47/61
A61K 47/68
A61K 47/60
A61P 9/10
A61P 37/06
A61P 3/06
A61P 19/02
A61P 31/04
A61K 31/165
A61K 31/167
A61K 31/417
A61K 31/4985
A61K 31/5383
A61K 31/58
A61K 38/14
A61K 39/395
Abstract:
Provided herein are antibodies and antigen-binding fragments that bind MSR1 and methods of use thereof. According to certain embodiments, the antibodies bind human MSR1 with high affinity. In certain embodiments, the antibodies bind MSR1 without blocking, or blocking less than 90%, of modified LDL binding to MSR1. In some embodiments, the antibodies bind cell surface expressed-MSR1 and are internalized. The antibodies of the invention may be fully human antibodies. The invention includes anti-MSR1 antibodies, or antigen-binding fragments thereof, conjugated to drugs or therapeutic compounds.

Crnn Loss Of Function Rodent Model

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US Patent:
20210100227, Apr 8, 2021
Filed:
Oct 2, 2020
Appl. No.:
17/061978
Inventors:
- Tarrytown NY, US
Sokol HAXHINASTO - Brookfield CT, US
Zaruhi HOVHANNISYAN - Hoboken NJ, US
International Classification:
A01K 67/027
A61K 49/00
Abstract:
This disclosure relates to a genetically modified rodent and use thereof as a rodent model. More specifically, this disclosure relates to rodent (e.g., mouse or rat) comprising a loss of function mutation in an endogenous Crnn (cornulin) gene, and to use of such a rodent animal as a rodent model of skin inflammation disorders (e.g., psoriasis),

Non-Human Animal Models Of Ditra Disease And Uses Thereof

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US Patent:
20200015462, Jan 16, 2020
Filed:
Jul 16, 2019
Appl. No.:
16/512949
Inventors:
- Tarrytown NY, US
Alexander O. Mujica - Elmsford NY, US
Ka-Man Venus Lai - San Francisco CA, US
Sokol Haxhinasto - Brookfield CT, US
Zaruhi Hovhannisyan - Hoboken NJ, US
International Classification:
A01K 67/027
C07K 16/24
C07K 16/28
C12N 15/85
Abstract:
This disclosure relates to genetically modified rodent animals and rodent models of human diseases. More specifically, this disclosure relates to genetically modified rodents whose genome comprises a humanized Il1rl2 gene (coding for the IL1rl2 subunit of the IL-36R protein) and human IL-36α, β and γ ligand genes. The genetically modified rodents disclosed herein display enhanced skin and intestinal inflammation as a preclinical model of psoriasis and IBD, respectively, and serve as a rodent model of human DITRA disease.

Anti-Msr1 Antibodies And Methods Of Use Thereof

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US Patent:
20190367631, Dec 5, 2019
Filed:
May 8, 2019
Appl. No.:
16/407099
Inventors:
- Tarrytown NY, US
Viktoria Gusarova - Pleasantville NY, US
Amy Han - Hockessin DE, US
Sokol Haxhinasto - Brookfield CT, US
Christos Kyratsous - Irvington NY, US
Andrew J. Murphy - Croton-on Hudson NY, US
Thomas Nittoli - Pearl River NY, US
William Olson - Yorktown Heights NY, US
Matthew Sleeman - White Plains NY, US
Anna Zumsteg - Elmsford NY, US
International Classification:
C07K 16/28
A61K 47/68
A61K 31/58
A61K 31/165
A61K 31/167
A61K 31/417
A61K 31/5383
A61K 31/4985
A61K 47/61
A61K 47/60
A61P 9/10
A61P 19/02
A61P 3/06
A61P 31/04
A61K 38/14
A61K 39/395
A61P 37/06
Abstract:
Provided herein are antibodies and antigen-binding fragments that bind MSR1 and methods of use thereof. According to certain embodiments, the antibodies bind human MSR1 with high affinity. In certain embodiments, the antibodies bind MSR1 without blocking, or blocking less than 90%, of modified LDL binding to MSR1. In some embodiments, the antibodies bind cell surface expressed-MSR1 and are internalized. The antibodies of the invention may be fully human antibodies. The invention includes anti-MSR1 antibodies, or antigen-binding fragments thereof, conjugated to drugs or therapeutic compounds.
Sokol A Haxhinasto from Brookfield, CT, age ~48 Get Report