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William James Pavan

from East New Market, MD
Age ~61
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Also known as:
William J Pavan, William H Pavan, Bill Pavan, William Paven, Pavan Bill
Phone and address:
5645 Beach Haven Rd, East New Market, MD 21631
Related to:
Lillian Baxter, 56Robert BeveridgeAlison Northridge, 35Kelli J Nidositko, 52
Connected to:
Josyula Pavan, 42Konanur Pavan, 41Meredith L Pavan, 44Shelby L Pavan, 34Shrestha Pavan, 33Sophie Pavan, 96Venkata Pavan, 41Reena P Pavana, 52Shalin M Pavanacherry, 41Darsi Pavani, 43

William Pavan Phones & Addresses

  • 5645 Beach Haven Rd, E New Market, MD 21631
  • East New Market, MD
  • 8541 Hawk Run Ct, Montgomery Village, MD 20886 (240) 683-8916
  • Gaithersburg, MD
  • 7724 Warbler Ln, Derwood, MD 20855 (301) 963-6214
  • East Windsor, NJ
  • Pasadena, MD
  • Yorktown Heights, NY
  • Mahopac, NY
  • 7724 Warbler Ln, Derwood, MD 20855 (301) 467-6570

Work

Position: Sales Occupations

Education

Degree: Associate degree or higher

Publications

Us Patents

Genes For Niemann-Pick Type C Disease

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US Patent:
7045675, May 16, 2006
Filed:
Jul 29, 2002
Appl. No.:
10/208731
Inventors:
Eugene D Carstea - Woburn MA, US
Danilo A. Tagle - Gaithersburg MD, US
Jill A. Morris - Chalfont PA, US
Peter G. Pentchev - Kensington MD, US
William J. Pavan - Derwood MD, US
Melissa A. Ashlock - Mont Vernon NH, US
Stacie K. Loftus - Burtonsville MD, US
Jessie Gu - Cambridge MA, US
Assignee:
The United States of America as represented by the Department of Health and Human Services - Washington DC
International Classification:
A01K 67/00
C12N 15/00
C12N 1/20
C12P 21/02
G01N 33/567
US Classification:
800 8, 800 18, 435354, 435 721, 435 691, 4352523, 435455, 435463, 530300, 530350, 514 2, 536 235
Abstract:
A gene for type C Niemann-Pick disease (NP-C) is disclosed, along with the amino acid sequence of the encoded peptide. Applications which are made possible by the present invention include detection of NP-C carriers and diagnosis of NP-C sufferers. The murine ortholog of the human gene is also disclosed.

Alteration Of Rab38 Function To Modulate Mammalian Pigmentation

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US Patent:
20060252036, Nov 9, 2006
Filed:
Jan 17, 2003
Appl. No.:
10/501611
Inventors:
William Pavan - Derwood MD, US
Stacie Loftus - Great Falls VA, US
International Classification:
C12Q 1/68
US Classification:
435006000
Abstract:
The present invention relates to compositions and methods involving melanocytes. In particular, the present invention provides compositions and methods involving RAB38 and mutant RAB38, suitable for use in modulation of pigmentation and for use in determining the means to diagnose and/or treat conditions associated with disorders in pigmentation.

Genes For Niemann-Pick Type C Disease

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US Patent:
6426198, Jul 30, 2002
Filed:
Jun 1, 1999
Appl. No.:
09/462136
Inventors:
Eugene D. Carstea - Woburn MA
Danilo A. Tagle - Gaithersburg MD
Jill A. Morris - Chalfont PA
Peter G. Pentchev - Kensington MD
William J. Pavan - Derwood MD
Melissa A. Ashlock - Mont Vernon NH
Stacie K. Loftus - Burtonsville MD
Jessie Gu - Cambridge MA
Assignee:
The United States of America as represented by the Secretary of the Department of Health and Human Services - Washington DC
International Classification:
C07K 100
US Classification:
435 691, 435 6, 435 72, 435 2431, 435 721, 4352523, 4353201, 435325, 530350, 536 235, 436501, 514 2
Abstract:
A gene for type C Niemann-Pick disease (NP-C) is disclosed, along with the amino acid sequence of the encoded peptide. Applications which are made possible by the present invention include detection of NP-C carriers and diagnosis of NP-C sufferers. The murine ortholog of the human gene is also disclosed.

Viral Gene Therapy As Treatment For Cholesterol Storage Disease Or Disorder

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US Patent:
20210113635, Apr 22, 2021
Filed:
Sep 25, 2020
Appl. No.:
17/033166
Inventors:
- Bethesda MD, US
Randy Chandler - Washington DC, US
William J. Pavan - Derwood MD, US
Assignee:
The United States of America,as represented by the Secretary,Department of Health and Human Services - Bethesda MD
International Classification:
A61K 35/761
A61K 48/00
C12N 15/86
A61P 25/28
A61P 3/00
C07K 14/075
C12N 7/04
C12N 15/861
Abstract:
Provided herein are compositions and methods for the viral gene therapy (e.g., AAV-directed gene therapy) of cholesterol storage diseases or disorders, such as Niemann-Pick disease, Type C

Codon-Optimized Human Npc1 Genes For The Treatment Of Niemann-Pick Type C1 Deficiency And Related Conditions

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US Patent:
20200377906, Dec 3, 2020
Filed:
Jun 20, 2018
Appl. No.:
16/623863
Inventors:
- Bethesda MD, US
William J. Pavan - Derwood MD, US
Randy J. Chandler - Chevy Chase MD, US
Assignee:
The United States of America,as represented by the Secretary,Department of Health and Human Services - Bethesda MD
International Classification:
C12N 15/86
C12N 15/52
C12N 15/62
C12N 15/67
Abstract:
The present disclosure provides compositions for viral gene therapy, e.g. Adeno-Associated virus-directed gene therapy, and methods of using the same for the treatment and/or prevention of cholesterol storage diseases or disorders, such as Niemann-Pick disease, Type C.

Viral Gene Therapy As Treatment For Cholesterol Storage Disease Or Disorder

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US Patent:
20180104289, Apr 19, 2018
Filed:
Apr 7, 2016
Appl. No.:
15/565065
Inventors:
- Bethesda MD, US
Randy Chandler - Washington DC, US
William J. Pavan - Derwood MD, US
Assignee:
Services - Bethesda MD
International Classification:
A61K 35/761
A61K 48/00
C07K 14/075
C12N 7/04
C12N 15/861
A61P 25/28
A61P 3/00
Abstract:
Provided herein are compositions and methods for the viral gene therapy (e.g., AAV-directed gene therapy) of cholesterol storage diseases or disorders, such as Niemann-Pick disease, Type C.

Identification Of Two Novel Biomarkers For Niemann-Pick Disease Type C

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US Patent:
20140370521, Dec 18, 2014
Filed:
Dec 14, 2012
Appl. No.:
14/365398
Inventors:
- Rockville MD, US
Celine V. M. Cluzeau - Bethesda MD, US
Dawn E. Watkins-Chow - Kensington MD, US
Christopher A. Wassif - Edgewood MD, US
William J. Pavan - Derwood MD, US
International Classification:
G01N 33/68
G01N 33/573
US Classification:
435 74, 436501, 5303898
Abstract:
This invention provides novel biomarkers for Niemann-Pick disease, type C (NPC). In an exemplary embodiment, the invention provides methods for identifying a subject as having NPC. In embodiments, the methods involve detecting the level of biomarker selected from the group comprising i) galectin-3 (LGALS3); ii) cathepsin D (CTSD); iii) LGALS3 and CTSD; and iv) LGALS3 and/or CTSD in combination at least one additional NPC associated biomarker in a sample obtained from the subject. In embodiments, the methods involve comparing the level of biomarker to a reference.
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William James Pavan from East New Market, MD, age ~61 Get Report