US Patent:
20230022524, Jan 26, 2023
Inventors:
- New York NY, US
Steven Burakoff - New York NY, US
H. Umit Kaniskan - New York NY, US
Sansana Sawasdikosol - New York NY, US
He Chen - New York NY, US
Joshua Brody - New York US, US
Nina Bhardwaj - New York NY, US
International Classification:
A61K 47/55
A61K 39/395
A61K 47/54
A61P 35/00
Abstract:
Disclosed are Hematopoietic Progenitor Kinase 1 (HPK1) degradation/disruption compounds including a HPK1 ligand, a degradation/disruption tag and a linker, and methods for use of such compounds in the treatment of HPK1-mediated diseases.