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Ilia V Davydov

from Rockville, MD
Age ~58

Ilia Davydov Phones & Addresses

  • 15302 Diamond Cove Ter, Rockville, MD 20850 (301) 869-3668 (301) 869-3710
  • 15302 Diamond Cove Ter APT 11, Rockville, MD 20850 (301) 869-3668
  • 13823 Grey Colt Dr, Gaithersburg, MD 20878
  • 435 Side Dr, Gaithersburg, MD 20878
  • 9890 Washingtonian Blvd, Gaithersburg, MD 20878
  • 21 Summit Ave, Gaithersburg, MD 20877
  • North Potomac, MD
  • Pasadena, CA

Work

Company: Meso scale discovery 2011 Position: Director, critical reagents

Education

Degree: Ph.D. School / High School: Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, RAS 1988 to 1992 Specialities: Molecular Biology

Industries

Biotechnology

Resumes

Resumes

Ilia Davydov Photo 1

Director, Critical Reagents

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Location:
9238 Gaither Rd, Gaithersburg, MD 20877
Industry:
Biotechnology
Work:
Meso Scale Discovery since 2011
Director, Critical Reagents

Meso Scale Discovery 2000 - 2011
Senior Scientist

California Institute of Technology - Pasadena, CA 1995 - 2000
Senior Research Fellow

German Cancer Research Center - Heidelberg, Germany 1992 - 1995
Guest Scientist
Education:
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, RAS 1988 - 1992
Ph.D., Molecular Biology
Московский Государственный Университет им. М.В. Ломоносова (МГУ) / Lomonosov Moscow State University (MSU) 1983 - 1988
B.S./M.S., Biochemistry

Publications

Us Patents

Deazaflavin Compounds And Methods Of Use Thereof

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US Patent:
7498336, Mar 3, 2009
Filed:
Feb 12, 2004
Appl. No.:
10/545547
Inventors:
Allan M. Weissman - Bethesda MD, US
Karen H. Vousden - Glasgow, GB
Jane P. Jensen - Potomac MD, US
Yili Yang - Montgomery Village MD, US
Shengyun Fang - Potomac MD, US
Douglas Woods - Gaithersburg MD, US
John H. Kenten - Boyds MD, US
Ilia Davydov - North Potomac MD, US
Yassamin J. Safiran - Potomac MD, US
Pankaj Oberoi - Rockville MD, US
Assignee:
The United States of America as represented by the Secretary, Department of Health and Human Services - Washington DC
BioVeris Corporation - Gaithersburg MD
International Classification:
A01N 43/54
A61K 31/505
C07D 239/00
C07D 471/00
C07D 487/00
C07D 491/00
US Classification:
514267, 544250
Abstract:
The present invention features 5-deazaflavin compounds, pharmaceutical compositions of 5-deazaflavin compounds and methods of treating a patient suffering from cancer, the method comprising administering to a patient one or more 5-deazaflavin compounds of the invention.

Substrates Of N-End Rule Ubiquitylation And Methods For Measuring The Ubiquitylation Of These Substrates

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US Patent:
7608682, Oct 27, 2009
Filed:
Oct 28, 2003
Appl. No.:
10/693999
Inventors:
Ilia Davydov - North Potomac MD, US
John H. Kenten - Boyds MD, US
Hans Biebuyck - Rockville MD, US
Pankaj Oberoi - Rockville MD, US
Assignee:
Meso Scale Technologies LLC - Gaithersburg MD
International Classification:
C07K 14/00
C12P 1/00
US Classification:
530300, 514 2, 435 41
Abstract:
The present invention relates to methods, compositions, compounds and kits for detecting, measuring and modulating protein ubiquitylation via the N-end rule pathway and for identifying novel substrates, enzymes and modulators of N-end rule ubiquitylation. The present invention also relates to specific substrates of N-end rule ubiquitylation as well as activated fragments of these substrates, proteases that expose N-degrons in these substrates, ubiquitin ligases that ubiquitylate these substrates and inhibitors of the ubiquitylation of these substrates.

Substrates Of N-End Rule Ubiquitylation And Methods For Measuring The Ubiquitylation Of These Substrate

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US Patent:
8530408, Sep 10, 2013
Filed:
Oct 27, 2009
Appl. No.:
12/606787
Inventors:
Ilia Davydov - North Potomac MD, US
John H. Kenten - Boyds MD, US
Hans Biebuyck - Rockville MD, US
Pankaj Oberoi - Rockville MD, US
Assignee:
Meso Scale Technologies LLC - Gaithersburg MD
International Classification:
C07K 14/00
US Classification:
514 2, 530300
Abstract:
The present invention relates to methods, compositions, compounds and kits for detecting, measuring and modulating protein ubiquitylation via the N-end rule pathway and for identifying novel substrates, enzymes and modulators of N-end rule ubiquitylation. The present invention also relates to specific substrates of N-end rule ubiquitylation as well as activated fragments of these substrates, proteases that expose N-degrons in these substrates, ubiquitin ligases that ubiquitylate these substrates and inhibitors of the ubiquitylation of these substrates.

Methods, Reagents, Kits And Apparatus For Protein Function Analysis

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US Patent:
20030207290, Nov 6, 2003
Filed:
Sep 10, 2002
Appl. No.:
10/238960
Inventors:
John Kenten - Boyds MD, US
Hans Biebuyck - Rockville MD, US
Ilia Davydov - North Potomac MD, US
Nisar Pampori - Frederick MD, US
Steven Cheng - Rockville MD, US
Stefanie Nelson - Silver Spring MD, US
International Classification:
C12Q001/68
G01N033/53
G01N033/542
C12M001/34
US Classification:
435/006000, 435/007900, 435/287200
Abstract:
Apparatus, systems, system components, methods, compositions, and reagents for determining the function and activity of peptides and proteins and for identifying and characterizing molecules that affect these functions and activities. More specifically, methods and reagents used to determine the various activities of peptides and proteins including their binding specificity, binding activity, their enzymatic activity and their ability to act as substrates for enzymes. The disclosed methods are especially suited for the analysis of peptide and protein function where large numbers of peptides and proteins need to be analyzed.

Modulation Of Angiogenesis Through Targeting Of Cysteine Oxygenase Activity

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US Patent:
20040023311, Feb 5, 2004
Filed:
Mar 21, 2003
Appl. No.:
10/395048
Inventors:
Yong Kwon - Wexford PA, US
Ilia Davydov - North Potomac MD, US
Fangyong Du - New Haven CT, US
Alexander Varshavsky - La Canada CA, US
International Classification:
G01N033/53
G01N033/567
A61K031/00
US Classification:
435/007200, 514/001000
Abstract:
The invention provides methods and compositions for modulating angiogenesis in a subject. The methods of modulating angiogenesis in a subject include administering to the subject a modulator of N-terminal cysteine oxygenase activity. The invention also provides a method of identifying such a modulator and a method of in vitro screening for modulators of N-terminal cysteine oxygenase activity. Additionally, the invention provides a method of treating an angiogenesis-related disorder.

Deazaflavin Compounds And Methods Of Use Thereof

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US Patent:
20100048593, Feb 25, 2010
Filed:
Feb 23, 2009
Appl. No.:
12/390692
Inventors:
Allan M. Weissman - Bethesda MD, US
Karen H. Vousden - Glasgow, GB
Jane P. Jensen - Potomac MD, US
Yili Yang - Montgomery Village MD, US
Shengyun Fang - Potomac MD, US
Douglas Woods - Auckland, NZ
John H. Kenten - Boyds MD, US
Ilia Davydov - North Potomac MD, US
Yassamin J. Safiran - Potomac MD, US
Pankaj Oberoi - Rockville MD, US
Assignee:
Government of the US, as represented by the Secretary, Department of Health & Human Services - Rockville MD
BioVeris Corporation - Gaithersburg MD
International Classification:
A61K 31/519
C07D 239/70
A61P 35/00
US Classification:
514267, 544250
Abstract:
The present invention features 5-deazaflavin compounds, pharmaceutical compositions of 5-deazaflavin compounds and methods of treating a patient suffering from cancer, the method comprising administering to a patient one or more 5-deazaflavin compounds of the invention.

Methods Of Screening Antigen-Binding Molecules By Normalizing For The Concentration Of Antigen-Binding Molecule

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US Patent:
20210087709, Mar 25, 2021
Filed:
Feb 22, 2019
Appl. No.:
16/971752
Inventors:
- Rockville MD, US
Ilia V. DAVYDOV - Rockville MD, US
International Classification:
C40B 30/04
C07K 16/26
C07K 16/00
Abstract:
The invention provides singleplex and multiplex assays for screening of antigen-binding molecules for their affinity to antigens by normalizing for the concentration of the antigen-binding molecule.
Ilia V Davydov from Rockville, MD, age ~58 Get Report