Janet Hauser Phones & Addresses
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1430 Gascho Dr, Dayton, OH 45410 (937) 253-0046
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5519 Southwick St, Bethesda, MD 20817 (301) 530-6090
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Montgomery, OH
Work
Position:
Protective Service Occupations
Publications
Us Patents
Neurotrophic Components Of The Adnf I Complex
View pageUS Patent:
20090247457, Oct 1, 2009
Filed:
Aug 25, 2008
Appl. No.:
12/197915
Inventors:
DOUGLAS E. BRENNEMAN - NORTH WALES PA, US
RAQUEL CASTELLON - NORWALK CA, US
CATHERINE Y. SPONG - ARLINGTON VA, US
JANET M. HAUSER - BETHESDA MD, US
IIIANA GOZES - RAMAT-HASHARON, IL
RAQUEL CASTELLON - NORWALK CA, US
CATHERINE Y. SPONG - ARLINGTON VA, US
JANET M. HAUSER - BETHESDA MD, US
IIIANA GOZES - RAMAT-HASHARON, IL
Assignee:
SECRETARY OF THE DEPTARTMENT OF HEALTH AND HUMAN SERVICES - ROCKVILLE MD
RAMOT AT TEL-AVIV UNIVERSITY - TEL AVIV
RAMOT AT TEL-AVIV UNIVERSITY - TEL AVIV
International Classification:
A61K 38/17
C12N 5/00
A61K 38/10
A61K 38/08
A61P 25/28
A61P 25/32
A61P 15/00
A61P 25/00
C12N 5/00
A61K 38/10
A61K 38/08
A61P 25/28
A61P 25/32
A61P 15/00
A61P 25/00
US Classification:
514 12, 435377, 514 13, 514 15, 514 14
Abstract:
This invention relates to Activity Dependent Neurotrophic Factor I complex (ADNF I complex) and polypeptides of this complex, which produce their neurotrophic effects through multiple proteases intrinsic to the ADNF I complex. The invention also relates to pharmaceutical compositions comprising ADNF I complex polypeptides, as well as methods for reducing neuronal cell death in vitro and in vivo, methods for treating oxidative stress in a patient, methods for reducing a condition associated with fetal alcohol syndrome in a subject, and methods of enhancing learning and memory both pre- and post-natally, all of which methods use the ADNF I complex polypeptides of the invention.
Neurothrophic Components Of The Adnf I Complex
View pageUS Patent:
7427590, Sep 23, 2008
Filed:
Sep 12, 2002
Appl. No.:
10/489515
Inventors:
Douglas E. Brenneman - North Wales PA, US
Raquel Castellon - Norwalk CA, US
Catherine Y. Spong - Arlington VA, US
Janet M. Hauser - Bethesda MD, US
Illana Gozes - Ramat Hasharon, IL
Raquel Castellon - Norwalk CA, US
Catherine Y. Spong - Arlington VA, US
Janet M. Hauser - Bethesda MD, US
Illana Gozes - Ramat Hasharon, IL
Assignee:
The United States of America as represented by the Secretary of the Department of Health and Human Services - Washington DC
Ramot at Tel-Aviv University, Ltd. - Tel Aviv
Ramot at Tel-Aviv University, Ltd. - Tel Aviv
International Classification:
A61K 38/03
A61K 38/04
A61K 38/08
A61K 38/10
C07K 4/12
C07K 7/06
C07K 7/08
A61K 38/04
A61K 38/08
A61K 38/10
C07K 4/12
C07K 7/06
C07K 7/08
US Classification:
514 2, 514 13, 514 15, 530300, 530323, 530326, 530328
Abstract:
This invention relates to Activity Dependent Neurotrophic Factor I complex (ADNF I complex) and polypeptides of this complex, which produce their neurotrophic effects through multiple proteases intrinsic to the ADNF I complex. The invention also relates to pharmaceutical compositions comprising ADNF I complex polypeptides, as well as methods for reducing neuronal cell death in vitro and in vivo, methods for treating oxidative stress in a patient, methods for reducing a condition associated with fetal alcohol syndrome in a subject, and methods of enhancing learning and memory both pre- and post-natally, all of which methods use the ADNF I complex polypeptides of the invention.