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John W Forstrom

from Bow, WA
Age ~74
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Related to:
Robert Allen Olson, 58Carl E Forstrom, 72Robert HuntJennifer Simpson, 43
Connected to:
Erika M Forstrom, 48Joel S Forstrom, 72Marsha A Forstrom, 68Sharon N Forstrom, 75Shirley A Forstrom, 73Virginia Forstrom, 107Amanda J Forsyth, 47Anna B Forsythe, 44Beatrice M Forsythe, 68Billie H Forsyth, 69

John Forstrom Phones & Addresses

  • 4963 Roney Rd, Bow, WA 98232 (360) 766-8601
  • 12636 Blakely Ave, Seattle, WA 98177
  • 4963 Roney Rd, Bow, WA 98232

Work

Company: Zymogenetics inc. Position: V.p. bio-process development

Industries

Biotechnology

Resumes

Resumes

John Forstrom Photo 1

V.p. Bio-Process Development At Zymogenetics Inc. (Retired)

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Position:
V.P. Bio-Process Development at ZymoGenetics Inc.
Location:
Bow, Washington
Industry:
Biotechnology
Work:
ZymoGenetics Inc.
V.P. Bio-Process Development

Publications

Us Patents

Method For Activating Prethrombin-1

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US Patent:
8062876, Nov 22, 2011
Filed:
Dec 21, 2006
Appl. No.:
12/097027
Inventors:
Robert W. Mallett - Ravensdale WA, US
Christopher J. Stenland - Stanwood WA, US
Jonathon C. Boone - Kenmore WA, US
John W. Forstrom - Seattle WA, US
Karen S. De Jongh - Seattle WA, US
Assignee:
Zymogenetics, Inc. - Princeton NJ
International Classification:
C12N 9/74
US Classification:
435214
Abstract:
Methods for converting prethrombin-1 to thrombin are disclosed. An aqueous solution of prethrombin-1 is applied to oscutarin-C immobilized on a solid support so as to provide from 500 mg to 4000 mg of prethrombin-1 per mL of the solid support and a contact time between the prethrombin-1 and the oscutarin-C of from 1. 8 to 3. 5 minutes. The resulting active thrombin may be captured on an ion exchange chromatography medium or an affinity chromatography medium.

Neutrophil Chemoattractants

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US Patent:
52410498, Aug 31, 1993
Filed:
Dec 22, 1989
Appl. No.:
7/455698
Inventors:
Richard B. Goodman - Kirkland WA
John W. Forstrom - Seattle WA
Thomas R. Martin - Mercer Island WA
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
A61K 3702
C07K 302
C07K 1506
US Classification:
530350
Abstract:
Substantially pure porcine proteins having chemoattractant activity for neutrophils and methods for preparing the proteins are provided. These proteins are useful within compositions for enhancing neutrophil chemotaxis, such as in promoting the formation of granulation tissue. The proteins may also be used within methods for developing inflammatory and anti-inflammatory agents.

Materials And Methods For Determining Ob Protein In A Biological Sample

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US Patent:
58277340, Oct 27, 1998
Filed:
Oct 4, 1995
Appl. No.:
8/540242
Inventors:
David S. Weigle - Bainbridge Island WA
Joseph L. Kuijper - Bothell WA
John W. Forstrom - Seattle WA
Joyce M. Lehner - Seattle WA
Assignee:
University of Washington - Seattle WA
Zymogenetics, Inc. - Seattle WA
International Classification:
C12N 500
C07K 1600
US Classification:
435325
Abstract:
Methods for determining ob protein in a biological sample are disclosed. In a preferred embodiment, the biological samples are analyzed using an ELISA capable of detecting and quantitating ob protein.

Appetite Supression Factor And Related Methods

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US Patent:
58589678, Jan 12, 1999
Filed:
Sep 19, 1997
Appl. No.:
8/938001
Inventors:
David S. Weigle - Bainbridge Island WA
Joseph L. Kuijper - Bothell WA
John W. Forstrom - Seattle WA
Assignee:
University of Washington - Seattle WA
Zymogenetics, Inc. - Seattle WA
International Classification:
A01N 3718
A61K 3700
C12P 2106
US Classification:
514 2
Abstract:
Methods for identifying factors that regulate appetite are disclosed. Preferably, the methods feature determinination of decreased food consumption in selected recipient mammals following administration of a test sample. A product having appetite suppressing activity is also described. In addition, methods for reducing food consumption in a mammal, featuring administration of a pharmaceutical composition comprising a representative appetite suppression factor, are disclosed.

Purified Thrombopoietin And Method Of Making It

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US Patent:
59860499, Nov 16, 1999
Filed:
Jun 1, 1995
Appl. No.:
8/457254
Inventors:
John W. Forstrom - Seattle WA
Si Lok - Seattle WA
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
A61K 3800
C07K 100
US Classification:
530344
Abstract:
Purified mammalian thrombopoietin proteins and methods of making them are disclosed. The proteins are characterized by a M. sub. r =70,000. +-. 10,000 daltons as determined by SDS-polyacrylamide gel electrophoresis under denaturing conditions and are at least 90% pure with respect to contaminating proteins. The proteins can be prepared by a method in which thrombopoietin is adsorbed to and eluted from a polypeptide comprising a ligand-binding domain of an MPL receptor, then the eluted thrombopoietin is fractionated by anion exchange chromatography.

Method For Purifying Thrombopoietin

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US Patent:
57445877, Apr 28, 1998
Filed:
Jun 7, 1995
Appl. No.:
8/484246
Inventors:
Andrew R. Alaska - Issaquah WA
William Downey - Seattle WA
John W. Forstrom - Seattle WA
Linh Phan - Seattle WA
Assignee:
ZymoGenetics, Inc. - Seattle WA
International Classification:
A61K 3824
A61K 3827
C04K 100
C04K 1400
US Classification:
530399
Abstract:
Methods of removing protein contaminants from a solution comprising thrombopoietin are disclosed. The solution is exposed to hydroxyapatite, whereby protein contaminants are bound to the hydroxyapatite and the thrombopoietin remains substantially unbound, and the unbound thrombopoietin is recovered. The use of hydroxyapatite is advantageously combined with other purification and concentration techniques, including ion-exchange chromatography, ligand affinity chromatography, hydrophobic interaction chromatography, ultrafiltration, and differential precipitation.
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John W Forstrom from Bow, WA, age ~74 Get Report