US Patent:
20120020914, Jan 26, 2012
Inventors:
Joseph M. Bay - Palo Alto CA, US
Bruce K. Patterson - Palo Alto CA, US
Nelson Teng - Hillsborough CA, US
Assignee:
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNVERSITY - PALO ALTO CA
International Classification:
A61K 38/19
A61P 15/00
A61P 35/00
A61P 31/20
Abstract:
Embodiments of the invention are related to leukemia inhibitory factor (LIF) for use in repressing human papillomavirus (HPV) transcription. Processes and related kits are described for treating a HPV-associated papillomatous proliferation, for treating a HPV-associated genital, anal, vulvar, penile, oral, or laryngeal wart, for treating HPV-associated cervical dysplasia or cervical cancer, and for repressing HPV transcription, by administering LIF to a patient in need thereof. A related embodiment is treatment of HPV-16 by use of LIF.