Inventors:
Rodney Bush - Mason OH, US
Paul Hershberger - Maineville OH, US
Judith Young - Cincinnati OH, US
Bhavani Kasibhatla - Hamilton OH, US
Assignee:
The Procter & Gamble Company - Cincinnati OH
International Classification:
A61K031/4709
A61K031/454
A61K031/428
A61K031/423
A61K031/4184
A61K031/405
C07D417/02
C07D413/02
C 07D 4 3/02
US Classification:
514/314000, 514/323000, 514/367000, 514/375000, 514/394000, 514/414000, 514/419000, 546/176000, 546/198000, 546/199000, 548/152000, 548/217000, 548/304700, 548/304400, 548/465000, 548/509000
Abstract:
The invention provides novel compounds selected from the group consisting of: The compounds of the present invention are useful for the treatment and prevention of a variety of diseases and conditions associated with undesirable or abnormal inflammatory responses, such as ischemia-reperfusion injury. Accordingly, the invention further provides pharmaceutical compositions comprising these compounds. The invention still further provides methods of treatment or prevention for the above disorders using theses compounds or the compositions containing them.
