Yi I Liu

7375203, May 20, 2008

Apr 6, 2005

11/099855

Christopher M. Flores - Lansdale PA, US
Yi Liu - Jenkintown PA, US
Mary Lou Lubin - Norristown PA, US
Ning Qin - Blue Bell PA, US

Janssen Pharmaceutica N.V. - Beerse

C07H 21/02
C07H 21/04

536 231, 536 232, 536 234, 536 235

The present invention provides nucleic acid and polypeptide sequences describing a novel canine cold- and menthol-sensitive receptor, herein named as canine CMR1 (cCMR1). The isolated nucleic acid or polypeptide molecule of the invention can be used in detection assays and screening assays.

8562809, Oct 22, 2013

Oct 2, 2009

13/122403

Yi Liu - Bethesda MD, US
Gregory F. Payne - Hunt Valley MD, US
W. Lee Meyer - Baltimore MD, US

University of Maryland, College Park - College Park MD

C25D 9/02

205229, 205317

A method of forming a bioelectronic device including a protein on an electrically conductive substrate, by electrodepositing aminopolysaccharide chitosan on the substrate while applying a cathodic voltage to the substrate, to form an aminopolysaccharide chitosan film thereon, applying an anodic voltage to the substrate in the presence of NaCl to activate the aminopolysaccharide chitosan film so that it is reactive with protein. The method also optionally includes reacting the aminopolysaccharide film, after activation thereof, with the protein, so that the protein assembles on and is coupled to the substrate, thereby forming a bioelectronic device. The protein can include single or multiple protein species, and including biosensing proteins. Additional methods include biosensing of electrochemically active compounds either present in a sample or generated during a biological recognition event and devices useful in such methods. The resulting devices are useful as sensors in hand-held devices, textiles, garments and the like.

20120103822, May 3, 2012

Apr 27, 2010

13/266433

Yi Liu - Bethesda MD, US
Gregory F. Payne - Hunt Valley MD, US
Xiaohua Yang - Ardmore OK, US

UNIVERSITY OF MARYLAND COLLEGE PARK - College Park MD

C25D 9/02
G01N 33/53
C12N 13/00

205317, 4351731, 435 71

Methods for the generation of hydrogels formed by electrodeposition of an electroaddressable polymer are described. The hydrogels may contain one or more cell populations electroaddressed or electroaddressable to a location within the hydrogel and where the cells of the cell populations are entrapped by the hydrogel and are capable of expansion within the hydrogel and may be releasable from the hydrogel. Further provided are electroaddressable polysaccharide blends for the in-film expansion of a cell population, allowing probing of the cells and formation of immunocomplexes. Further provided are methods of using hydrogels containing electroaddressed or electroaddressable cell populations in in-film bioprocessing methods such as cell-based biosensing, protein-based biosensing, and in studies of cell signaling.

20190350817, Nov 21, 2019

May 17, 2019

16/414986

- York PA, US
Christos Angeletakis - Bear DE, US
Yi Liu - Dover DE, US
Joachim E. Klee - Radolfzell, DE
Christoph Weber - Konstanz, DE
Xin Huo - Dover DE, US

DENTSPLY SIRONA Inc. - York PA

A61K 6/10
C08F 283/12

A light-curable dental impression material comprising(b) a particulate filler; and(c) a photoinitiator.

20190167116, Jun 6, 2019

Nov 15, 2018

16/192229

Yu Chen - College Park MD, US
Qinggong Tang - College Park MD, US
Udayakumar Kanniyappan - Hyattsville MD, US
Lin Z. Li - Aston PA, US
He Xu - Lansdowne PA, US
Yi Liu - College Park MD, US
Emily Conant - Philadelphia PA, US

A61B 5/00
A61B 1/07
A61B 1/04
A61B 1/06
A61B 1/00
A61B 10/02

In accordance with aspects of the present disclosure, an exemplary system includes a hollow probe having a lumen containing one or more excitation optical fiber(s) and one or more imaging optical fiber(s) where the probe is sized to access a person's body, a first light source optically coupled to the excitation fiber(s) and configured to emit light that excites fluorescence of NADH in breast tissue, a second light source optically coupled to the excitation fiber(s) and configured to emit light that excites fluorescence of FAD in tissue such as breast tissue, an image capturing device optically coupled to the imaging fiber(s), and a controller configured to control the first light source and the image capturing device to capture NADH fluorescence signals/intensities while the probe is within the person's body and control the second light source and the image capturing device to capture FAD fluorescence signals/intensities while the probe is within the person's body.