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Alison Joly

from San Mateo, CA
Age ~61

Alison Joly Phones & Addresses

  • 3205 Monterey St, San Mateo, CA 94403 (650) 574-8177
  • 3135 Campus Dr, San Mateo, CA 94403
  • Los Angeles, CA
  • Gainesville, FL

Work

Position: Professional/Technical

Resumes

Resumes

Alison Joly Photo 1

Senior Vice President Program And Alliance Management

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Location:
San Francisco, CA
Industry:
Biotechnology
Work:
Cytomx Therapeutics
Senior Vice President Program and Alliance Management

Cytomx Therapeutics
Vice President Alliance Management

Exelixis Aug 2011 - Oct 2014
Vice President Program Managment

Exelixis Jan 2008 - Aug 2011
Vice President Clinical Operations and Program Management

Exelixis Jan 2007 - Jan 2008
Vice President Program Management
Education:
University of Liverpool
Doctorates, Doctor of Philosophy, Biochemistry, Philosophy
Skills:
Clinical Development
Biotechnology
Drug Discovery
Drug Development
Pharmaceutical Industry
Clinical Trials
Oncology
Life Sciences
Fda
Ind
Biopharmaceuticals
Biomarkers
Cro
Cross Functional Team Leadership
Program Management
Gcp
Ctms
Edc
Good Clinical Practice
Cro Management
Lifesciences
U.s. Food and Drug Administration
Electronic Data Capture
Clinical Trial Management System
Alison Joly Photo 2

Vice President Program Management At Exelixis

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Position:
Vice President Program Management at Exelixis
Location:
San Francisco Bay Area
Industry:
Biotechnology
Work:
Exelixis since Aug 2011
Vice President Program Management

Exelixis 2000 - 2010
Vice President Clinical Operations and Program Management

Scios 1997 - 2000
Staff Scientist

Publications

Us Patents

Agonists And Antagonists Of Peripheral-Type Benzodiazepine Receptors

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US Patent:
6342495, Jan 29, 2002
Filed:
Dec 15, 1999
Appl. No.:
09/461780
Inventors:
Alison Joly - San Mateo CA
George F. Schreiner - Los Altos Hills CA
Lawrence W. Stanton - Redwood City CA
R. Tyler White - Fremont CA
Assignee:
Scios, Inc. - Sunnyvale CA
International Classification:
A61K 3155
US Classification:
514221, 514307
Abstract:
The invention concerns the use of agonists and antagonists of peripheral-type benzodiazcpine receptors (PTBR) in the diagnosis and treatment of cardiac hypertrophy and other circulatory conditions. The invention specifically concerns the use of PTBR antagonists in the prevention or treatment of decompensated cardiac hypertrophy and, eventually, heart failure. The invention also concerns the use of PTBR agonists in the management of conditions calling for increased blood flow or cardiac output, including injury or functional compromise of the heart, increased demand for physical exercise, or an acquired or inherited predisposition to cardiac contractile disfunction. Pharmaceutical compositions for the treatment of such conditions and screening methods to identify PTBR agonists and antagonists are also included.

Treatment Of Diseases Involving Cyst Formation

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US Patent:
6380183, Apr 30, 2002
Filed:
Dec 15, 1999
Appl. No.:
09/461910
Inventors:
George F. Schreiner - Los Altos Hills CA
Alison Joly - San Mateo CA
Lawrence W. Stanton - Redwood City CA
R. Tyler White - Fremont CA
Assignee:
Scios, Inc. - Sunnyvale CA
International Classification:
A61K 3155
US Classification:
51421106
Abstract:
The invention concerns the use of ligands of peripheral-type benzodiazepine receptors (PTBR) in the diagnosis and treatment of diseases involving cyst formation and in particular polycystic kidney disease. The invention further concerns the treatment of hypertension accompanying polycystic kidney disease, and pharmaceutical compositions and articles of manufacture for the treatment or diagnosis of the target disease or condition.

Human Ect2 Polypeptide

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US Patent:
6515109, Feb 4, 2003
Filed:
Oct 12, 2001
Appl. No.:
09/976239
Inventors:
Michael Martin Ollmann - Redwood City CA
Kevin Patrick Keegan - San Diego CA
Thomas J. Stout - San Francisco CA
David Matthews - San Francisco CA
Alison Joly - San Mateo CA
Assignee:
Exelixis, Inc. - S. San Francisco CA
International Classification:
C07K 1400
US Classification:
530350
Abstract:
Human Ect2 polypeptide, fragments and derivatives, along with vectors and host cells for expression and production of Ect2 polypeptide are provided. Various methods of screening for agents that modulate interaction of Ect2 with an Ect2 binding agent, including high throughput methods, are also provided.

Methods Of Screening For Agents That Modulate The Interaction Of Human Ect2 Polypeptide With An Ect2 Binding Target

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US Patent:
6630297, Oct 7, 2003
Filed:
Nov 7, 2002
Appl. No.:
10/289779
Inventors:
Michael Martin Ollmann - Redwood City CA
Kevin Patrick Keegan - San Diego CA
Thomas J. Stout - San Francisco CA
David Matthews - San Francisco CA
Alison Joly - San Mateo CA
Assignee:
Exelixis, Inc. - South San Francisco CA
International Classification:
C12Q 100
US Classification:
435 4, 435 71, 435 6, 435 721, 530350
Abstract:
Human Ect2 polypeptide, fragments and derivatives, along with vectors and host cells for expression and production of Ect2 polypeptide are provided. Various methods of screening for agents that modulate interaction of Ect2 with an Ect2 binding agent, including high throughput methods, are also provided.

Agonists And Antagonists Of Peripheral-Type Benzodiazepine Receptors

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US Patent:
6686354, Feb 3, 2004
Filed:
Dec 27, 2001
Appl. No.:
10/033189
Inventors:
Alison Joly - San Mateo CA
George F. Schreiner - Los Altos Hills CA
Lawrence W. Stanton - Redwood City CA
R. Tyler White - Fremont CA
Assignee:
Scios, Inc. - Sunnyvale CA
International Classification:
A61K 3155
US Classification:
514221, 514307
Abstract:
The invention concerns the use of agonists and antagonists of peripheral-type benzodiazepine receptors (PTBR) in the diagnosis and treatment of cardiac hypertrophy and other circulatory conditions. The invention specifically concerns the use of PTBR antagonists in the prevention or treatment of decompensated cardiac hypertrophy and, eventually, heart failure. The invention also concerns the use of PTBR agonists in the management of conditions calling for increased blood flow or cardiac output, including injury or functional compromise of the heart, increased demand for physical exercise, or an acquired or inherited predisposition to cardiac contractile disfunction. Pharmaceutical compositions for the treatment of such conditions and screening methods to identify PTBR agonists and antagonists are also included.

Methods For Detection And Use Of Differentially Expressed Genes In Disease States

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US Patent:
6709855, Mar 23, 2004
Filed:
Dec 15, 1999
Appl. No.:
09/461912
Inventors:
Lawrence W. Stanton - Redwood City CA
R. Tyler White - Fremont CA
Deborah L. Damm - Redwood City CA
John A. Lewicki - Los Gatos CA
Alison Joly - San Mateo CA
George F. Schreiner - Los Altos Hills CA
Assignee:
Scios, Inc. - Fremont CA
International Classification:
C12M 134
US Classification:
4352831, 4352872, 435 6, 536 243, 536 2433, 536 2431, 536 231
Abstract:
The present invention relates to methods and compositions for the detection, diagnosis, prevention and treatment of a disease, specifically cardiac, kidney or inflammatory disease, and related disorders. The present invention also relates to compositions and methods useful in the diagnosis, prevention and therapeutic treatment of a disease, specifically cardiac, kidney or inflammatory disease. Specifically, methods and compositions are provided for the diagnostic evaluation and prognosis of conditions involving a disease, specifically cardiac, kidney or inflammatory disease, for the identification of subjects exhibiting a predisposition to such conditions, for modulating the effect of these differentially expressed genes, for monitoring patients undergoing clinical evaluation for the prevention and treatment of a disease, specifically cardiac, kidney or inflammatory disease, and its disorders, and for monitoring the efficacy of compounds used in clinical trials.

Alpha-Ketoamide Inhibitors Of 20S Proteasome

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US Patent:
6781000, Aug 24, 2004
Filed:
Jul 19, 1999
Appl. No.:
09/356842
Inventors:
Lisa Wang - Burlingame CA
Robert T. Lum - Palo Alto CA
Steven R. Schow - Redwood City CA
Alison Joly - San Mateo CA
Suresh Kerwar - Westchester NY
Michael M Wick - Chestnut Hill MA
Assignee:
CV Theurapeutics, Inc.
International Classification:
C07D20912
US Classification:
548492, 548493, 548494, 548500
Abstract:
-ketoamide compounds useful for treating disorders mediated by 20S proteasome in mammals having the following formula: wherein X is Ar or ArâX wherein X is is âC O, or âCH COâ, and wherein Ar is phenyl, substituted phenyl, indole, substituted indoles, and any other heteroaryls; R , and R are each individually selected from the side chains of the known natural -amino acids and unnatural amino acids, hydrogen, 1-10 carbon linear and branched alkyl, 1-10 carbon linear and branched substituted alkyl, aryl, substituted aryl, 1-10 carbon linear, branched substituted aryl, alkoxyaryl, 3-8 carbon cycloalkyl, heterocycle substituted heterocycle, heteroaryl and substituted heteroaryl; X is selected from hydroxide, monoalkylamino, dialkylamino, alkoxide, arylkoxide and wherein X is hydroxide, arylamino, monoalkylamino, dialkylamino, alkoxide, or arylalkoxide; and R is selected from the known natural -amino acids, unnatural amino acids, hydrogen, 1-10 carbon linear and branched alkyl, 1-10 carbon linear and branched substituted alkyl, aryl, substituted aryl, 1-10 carbon linear and branched substituted aryl, alkoxyaryl, 3-8 carbon cycloalkyl, heterocycle, substituted heterocycle, heteroaryl and substituted heteroaryl.

Treatment Of Diseases Involving Cyst Formation

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US Patent:
20030008864, Jan 9, 2003
Filed:
Apr 30, 2002
Appl. No.:
10/136807
Inventors:
George Schreiner - Los Altos Hills CA, US
Alison Joly - San Mateo CA, US
Lawrence Stanton - Redwood City CA, US
R. White - Fremont CA, US
International Classification:
A61K031/5513
A61K031/337
US Classification:
514/221000, 514/449000
Abstract:
The invention concerns the use of ligands of peripheral-type benzodiazepine receptors (PTBR) in the diagnosis and treatment of diseases involving cyst formation and in particular polycystic kidney disease. The invention further concerns the treatment of hypertension accompanying polycystic kidney disease, and pharmaceutical compositions and articles of manufacture for the treatment or diagnosis of the target disease or condition.
Alison Joly from San Mateo, CA, age ~61 Get Report