US Patent:
20100035995, Feb 11, 2010
Inventors:
Mahendra G. Dedhiya - Pomona NY, US
Shashank Mahashabde - Kendell Park NJ, US
Yan Yang - Roslyn Heights NY, US
Anshu Goel - Levittown NY, US
Erhard Seiller - Nidderau, DE
Bernhard Hauptmeier - Gelnhausen, DE
Assignee:
MERZ PHARMA GMBH & CO. KGAA - FRANKFURT AM MAIN
International Classification:
A61K 31/13
Abstract:
The invention is directed to formulations of pharmaceutical compounds, such as the Cyclohexylamines and Aminoadamantanes which have antimicrobial properties. In particular, it is directed to aqueous based formulations with reduced amounts of preservatives which allow safe and convenient administration and flexible dosing and which, in the case of oral formulations, are easy to swallow. Optionally, the compositions contain components that provide the requisite stability and shelf life while reducing or avoiding incrustation of the composition around the container closure which leads to leaks and difficulty in opening the container.