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Binyuan Sun

from Needham, MA
Age ~52
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Also known as:
Binyuan Sunsun
Phone and address:
59 Richdale Rd, Needham, MA 02494
(781) 449-2507
Related to:
Winnie G Furman, 97Michael Paul Ruvo, 46
Connected to:
Alana Sun, 75Allan I Sun, 73Almagrace G Sun, 47Anni Sun, 32Baolin Sun, 61Bilin Sun, 35Boyan Sun, 32Brandon Sun, 42Burt H Sun, 58Caihong Sun, 47

Binyuan Sun Phones & Addresses

  • 59 Richdale Rd, Needham Hgts, MA 02494 (781) 449-2507
  • Needham, MA
  • 62 Sherman St, Roslindale, MA 02131 (617) 469-6317
  • 203 Gerry Rd, Chestnut Hill, MA 02467 (617) 327-7058
  • Boston, MA
  • 1 West Dr #601, Princeton, NJ 08540 (609) 683-0426
  • 601 West Dr #601, Princeton, NJ 08540

Publications

Us Patents

2-Aminothiazole-4-Carboxylic Amides As Protein Kinase Inhibitors

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US Patent:
8318735, Nov 27, 2012
Filed:
Oct 29, 2007
Appl. No.:
12/447710
Inventors:
Cliff C. Cheng - Cambridge MA, US
Xiaohua Huang - Malden MA, US
Thierry O. Fischmann - Scotch Plains NJ, US
Jose S. Duca - Cranford NJ, US
Matthew Richards - Somerville MA, US
Hongbo Zeng - Westford MA, US
Binyuan Sun - Chestnut Hill MA, US
Panduranga Adulla Reddy - Walpole MA, US
Lianyun Zhao - Burlington MA, US
Shuyi Tang - Quincy MA, US
Tzu T. Wong - Belmont MA, US
Praveen K. Tadikonda - Norwood MA, US
Luis E. Torres - Medford MA, US
M. Arshad Siddiqui - Newton MA, US
Michael P. Dwyer - Scotch Plains NJ, US
Kartik M. Keertikar - East Windsor NJ, US
Timothy J. Guzi - Sudbury MA, US
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
A61K 31/5355
A61K 31/496
C07D 401/14
C07D 403/14
C07D 413/14
US Classification:
5142358, 51425305, 51425306, 5142531, 544121, 544362, 544364
Abstract:
The present invention relates to novel Anilinopiperazine Derivatives of formula (I), compositions comprising the Anilinopiperazine Derivatives, and methods for using the Anilinopiperazine Derivatives for treating or preventing a proliferative disorder, an anti-proliferative disorder, inflammation, arthritis, a central nervous system disorder, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral disease, a fungal infection, or a disorder related to the activity of a protein kinase.

Pyrazolo[1,5-A]Pyrimidine Derivatives As Mtor Inhibitors

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US Patent:
8591943, Nov 26, 2013
Filed:
Apr 8, 2010
Appl. No.:
13/263193
Inventors:
Yongqi Deng - Newton MA, US
Binyuan Sun - Chestnut Hill MA, US
Hongbo Zeng - Westford MA, US
Matthew Richards - Somerville MA, US
Cliff C. Cheng - Cambridge MA, US
Yinyan Zhao - Rockville MD, US
Andrew McRiner - Melrose MA, US
Zhaoyang Meng - Lansdale PA, US
Yang Nan - Lansdale PA, US
Mehul F. Patel - Willow Grove PA, US
Iwona E. Wrona - Sharon MA, US
Panduranga Adulla Reddy - Walpole MA, US
Brian M. Eklov - Kalamazoo MI, US
Shuyi Tang - Belmont MA, US
Duan Liu - Arlington MA, US
Amit K. Mandal - Shrewsbury MA, US
Lianyun Zhao - Blue Bell PA, US
M. Arshad Siddiqui - Newton MA, US
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
A61K 9/127
A61K 39/395
A61K 31/554
A61K 31/541
A61K 31/5377
A61K 38/50
A61K 31/553
A61K 33/24
A61K 31/704
A61K 31/551
A61K 31/538
A61K 31/519
US Classification:
424450, 424 946, 4241381, 424623, 424649, 4241331, 51425216, 5142332, 5142555, 51421115, 5142522, 514218, 51421016, 514 34, 5142285, 514249, 5142593, 5142305, 51421018
Abstract:
The present invention provides methods for inhibiting mTOR using pyrazolo[1,5-a]pyrimidine compounds and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with mTOR using such compounds.

Fused Tricyclic Compounds As Novel Mtor Inhibitors

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US Patent:
8609675, Dec 17, 2013
Filed:
Jun 30, 2010
Appl. No.:
13/379685
Inventors:
Cliff C. Cheng - Cambridge MA, US
Hongbo Zeng - Westford MA, US
Yongqi Deng - Newton MA, US
Zhaoyang Meng - Lansdale PA, US
Lianyun Zhao - Blue Bell PA, US
Yang Nan - Malden MA, US
Binyuan Sun - Chestnut Hill MA, US
Duan Liu - Arlington MA, US
Panduranga A. Reddy - Walpole MA, US
M. Arshad Siddiqui - Newton MA, US
Assignee:
Merck Sharp & Dohme Corp. - Rahway NJ
International Classification:
A01N 43/54
C07D 491/00
US Classification:
514267, 544250
Abstract:
The present invention provides Fused Tricyclic Compounds of the Formula (I) wherein Q, R, R, R, and Rare as defined herein, and pharmaceutically acceptable salts of such Fused Tricyclic Compounds. The Fused Tricyclic Compounds are useful in the treatment of cancer and other proliferative disorders.

Bifunctional Glycopeptide Antibiotics And Combinatorial Libararies Thereof

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US Patent:
20030158093, Aug 21, 2003
Filed:
Aug 19, 2002
Appl. No.:
10/223569
Inventors:
Binyuan Sun - Princeton NJ, US
Zhong Chen - Princeton NJ, US
Daniel Kahne - Princeton NJ, US
International Classification:
A61K038/14
C07K009/00
US Classification:
514/008000, 530/322000
Abstract:
The present invention relates to a the design of a large class of antibiotics comprised of aglycones of vancomycin or derivatives of an aglycone of vancomycin attached to the anomeric site of moenomycin or a moenomycin derivative.

Anilinopiperazine Derivatives And Methods Of Use Thereof

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US Patent:
20120328691, Dec 27, 2012
Filed:
Oct 29, 2007
Appl. No.:
12/447712
Inventors:
Cliff C. Cheng - Cambridge MA, US
Xiaohua Huang - Malden MA, US
Thierry O. Fischmann - Scotch Plains NJ, US
Jose S. Duca - Cranford NJ, US
Matthew Richards - Somerville MA, US
Hongbo Zeng - Westford MA, US
Binyuan Sun - Chestnut Hill MA, US
Panduranga Adulla Reddy - Walpole MA, US
Tzu T. Wong - Belmont MA, US
Praveen K. Tadikonda - Norwood MA, US
M. Arshad Siddiqui - Newton MA, US
Marc A. Labroli - Moorestown NJ, US
Cory Poker - Bridgewater NJ, US
Timothy J. Guzi - Sudbury MA, US
International Classification:
A61K 31/496
A61K 31/55
C07D 417/12
A61K 31/454
A61K 31/427
A61K 31/541
A61K 31/506
A61K 31/497
C07D 471/10
A61K 31/438
A61K 31/4545
A61K 31/5377
C07D 498/10
A61K 31/5386
A61K 31/551
A61K 33/24
A61K 9/127
A61K 39/395
A61K 31/704
A61K 38/19
A61K 31/7068
A61K 38/50
A61K 38/20
A61K 38/21
A61P 35/00
A61P 35/02
A61N 5/10
C07D 417/14
US Classification:
424450, 544369, 51425402, 544364, 5142531, 540603, 5142171, 546209, 514326, 548200, 514365, 544 587, 5142278, 544295, 51425219, 544357, 51425211, 546 20, 514278, 51425404, 5142102, 546194, 514318, 546193, 544130, 5142368, 51425403, 546 16, 544 71, 544328, 514256, 540575, 514218, 540480, 424649, 4241331, 4241301, 514 34, 424 851, 514 49, 424 946, 424 852, 424 854, 600 1
Abstract:
The present invention relates to novel Anilinopiperazine Derivatives of Formula (I), compositions comprising the Anilinopiperazine Derivatives, and methods for using the Anilinopiperazine Derivatives for treating or preventing a proliferative disorder, cancer, an anti-proliferative disorder, inflammation, arthritis, a central nervous system disorder, a cardiovascular disease, alopecia, a neuronal disease, an ischemic injury, a viral disease, a fungal infection, or a disorder related to the activity of a protein kinase.

Novel Heterocyclic Compounds As Erk Inhbitors

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US Patent:
20130096084, Apr 18, 2013
Filed:
Jun 22, 2011
Appl. No.:
13/703250
Inventors:
Yongqi Deng - Newton MA, US
Liang Zhu - Waltham MA, US
Binyuan Sun - Chestnut Hill MA, US
Xiaohua Huang - Malden MA, US
Corey Bienstock - Natick MA, US
Alan B. Cooper - West Caldwell NJ, US
Xiaolei Gao - Bridgewater NJ, US
Xin Yao - Scotch Plains NJ, US
Hugh Y. Zhu - Warren NJ, US
Joseph M. Kelly - Parlin NJ, US
Sobhana Babu Boga - Scotch Plains NJ, US
Abdul-Basit Alhassan - Scotch Plains NJ, US
Jayaram R. Tagat - Westfield NJ, US
Umar Faruk Mansoor - Framingham MA, US
Kevin J. Wilson - Newton MA, US
Brendan M. O'Boyle - Boston MA, US
Matthew Hersh Daniels - Cambridge MA, US
Adam Schell - Newton MA, US
Phieng Siliphaivanh - Newton MA, US
Christian Fischer - Natick MA, US
International Classification:
C07D 401/14
A61K 45/06
C07D 405/14
A61K 31/454
A61K 31/55
A61K 31/551
C07D 401/12
C07D 409/14
C07D 417/14
A61K 31/506
C07D 471/04
C07F 7/18
A61K 31/695
C07D 413/14
A61K 31/5377
A61K 31/4545
US Classification:
514 63, 546194, 514318, 546199, 514322, 540524, 51421208, 540492, 514218, 544333, 514256, 546121, 514300, 546 14, 51421018, 544130, 5142345
Abstract:
The present invention provides a compound of the Formula I: (Formular I should be inserted here) or a pharmaceutically acceptable salt, solvate or ester thereof, wherein R, R1, R2 and R3 are as defined herein. The compounds are ERK inhibitors. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.

Fused Pyrazole Derivatives As Novel Erk Inhibitors

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US Patent:
20130172341, Jul 4, 2013
Filed:
Sep 12, 2011
Appl. No.:
13/821149
Inventors:
Yongqi Deng - Newton MA, US
Alan B. Cooper - West Caldwell NJ, US
Xiaolei Gao - Bridgewater NJ, US
Binyuan Sun - Chestnut Hill MA, US
James Wang - Westfield NJ, US
Liang Zhu - Waltham MA, US
International Classification:
C07D 471/04
C07D 405/04
C07D 401/04
C07D 401/14
C07D 417/14
US Classification:
5142342, 546120, 514303, 544127, 5462757, 514338, 548159, 514367, 546256, 514333, 546194, 514318
Abstract:
Disclosed are the ERK inhibitors of Formula (I): (Formula (I)) and the pharmaceutically acceptable salts thereof. All substitutents are as defined herein. Also disclosed are methods of treating cancer using the compounds of Formula (I).

Indazole Derivatives Useful As Erk Inhibitors

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US Patent:
20130261125, Oct 3, 2013
Filed:
Dec 16, 2011
Appl. No.:
13/994224
Inventors:
Xiaohua Huang - Brookline MA, US
Yongqi Deng - Newton MA, US
Liang Zhu - Waltham MA, US
Alan B. Cooper - West Caldwell NJ, US
Binyuan Sun - Chestnut Hill MA, US
Abdelghani Achab - Boston MA, US
International Classification:
A61K 31/4439
C07D 471/04
A61K 31/437
C07D 401/04
US Classification:
514247, 5462757, 514338, 546121, 514300, 546119, 514303, 544239
Abstract:
The present invention provides a compound of the Formula I, or a pharmaceutically acceptable salt, solvate or ester thereof, wherein R, R, R, R, m and are as defined herein. The compounds are ERK inhibitors. Also disclosed are pharmaceutical compositions that comprise the above compounds, and methods of treating cancer using the same.
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Binyuan Sun from Needham, MA, age ~52 Get Report