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Christopher D Kulczar

from Jersey City, NJ
Age ~35

Christopher Kulczar Phones & Addresses

  • 389 Washington St APT 18J, Jersey City, NJ 07302 (201) 418-8659
  • Bremen, IN
  • Lafayette, IN
  • Union, NJ

Publications

Us Patents

Pyrazole Pharmaceutical Composition

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US Patent:
20230070369, Mar 9, 2023
Filed:
Dec 18, 2020
Appl. No.:
17/785671
Inventors:
- Madison NJ, US
Christopher D. Kulczar - Jersey City NJ, US
Michelle H. Fung - Watchung NJ, US
Assignee:
Intervet Inc. - Madison NJ
International Classification:
A61K 31/4439
A61P 17/00
A61K 9/20
Abstract:
A pharmaceutical composition of pyrazole compound and a surfactant and a method of using the same to treat atopic dermatitis.

Blood Brain Barrier Models And Methods To Generate And Use The Same

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US Patent:
20210140947, May 13, 2021
Filed:
Dec 18, 2020
Appl. No.:
17/126226
Inventors:
- West Lafayette IN, US
Aimable Ngendahimana - West Lafayette IN, US
Christopher D. Kulczar - Bremen IN, US
Kelsey E. Lubin - Lafayette IN, US
Monika Lavan - Lafayette IN, US
Assignee:
Purdue Research Foundation - West Lafayette IN
International Classification:
G01N 33/50
C12N 5/079
C12N 5/071
Abstract:
The present disclosure generally relates to a process to prepare a cell culture system that mimics the structure of blood brain barrier (BBB) and are useful to study the functions thereof. In particular, the present invention relates to a direct-contact coculture and triculture systems prepared by plating BMECs on a pre-formed lawn of coculture of astrocytes and pericytes on the apical surface of a culture-chamber to achieve a truly direct contact triculture model for BBB. The cell culture systems disclosed herein are also useful for studying the functions of the blood brain barrier and predicting the efficacy and potential toxicity of a drug candidate.

Blood Brain Barrier Models And Methods To Generate And Use The Same

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US Patent:
20180067103, Mar 8, 2018
Filed:
Sep 7, 2017
Appl. No.:
15/697699
Inventors:
- West Lafayette IN, US
Aimable Ngendahimana - West Lafayette IN, US
Christopher D. Kulczar - Bremen IN, US
Kelsey E. Lubin - Lafayette IN, US
Monika Lavan - Lafayette IN, US
Assignee:
Purdue Research Foundation - West Lafayette IN
International Classification:
G01N 33/50
C12N 5/079
C12N 5/071
Abstract:
The present disclosure generally relates to a process to prepare a cell culture system that mimics the structure of blood brain barrier (BBB) and are useful to study the functions thereof. In particular, the present invention relates to a direct-contact coculture and triculture systems prepared by plating BMECs on a pre-formed lawn of coculture of astrocytes and pericytes on the apical surface of a culture-chamber to achieve a truly direct contact triculture model for BBB. The cell culture systems disclosed herein are also useful for studying the functions of the blood brain barrier and predicting the efficacy and potential toxicity of a drug candidate.
Christopher D Kulczar from Jersey City, NJ, age ~35 Get Report