Inventors:
Derek J. Hei - Concord CA
Assignee:
Cerus Corporation - Concord CA
International Classification:
A01N 102
US Classification:
435 2, 4351731, 4351739, 424529, 424530, 424531, 604 501, 604 502, 604 608, 604 609, 604 61, 604 615, 604262, 604403, 604406, 604408, 604409, 604410
Abstract:
Methods and devices for the removal of psoralens and psoralen photoproducts from blood products are described. The methods include contacting a psoralen- and irradiation-treated blood product with a resin capable of adsorbing psoralens and psoralen photoproducts. The removal process is particularly suitable for use with platelet concentrates and plasma because the process does not have a significant adverse effect on clotting factor function. The methods and devices can be incorporated with apheresis systems and other devices and procedures currently used to process blood products for transfusion.