Desmond C Adler

8315282, Nov 20, 2012

Oct 22, 2008

12/288715

Robert A. Huber - Schnaitsee, DE
James G. Fujimoto - Medford MA, US
Desmond C. Adler - Brookline MA, US

Massachusetts Institute of Technology - Cambridge MA

H01S 3/098
H01S 3/10

372 18, 372 20, 372 28, 372 98, 372 3801

A control system for improving and stabilizing Fourier domain mode locking (FDML) operation. The control system may also provide regulation of FDML operational parameters such as filter tuning, laser gain, polarization, polarization chromaticity, elliptical polarization retardance, and/or dispersion. The control system may be located internal to or external from the FDML laser cavity.

8582619, Nov 12, 2013

Mar 15, 2011

13/048441

Desmond Adler - Melrose MA, US

Lightlab Imaging, Inc. - Westford MA

H01S 3/08

372106, 372102, 372 98, 372 18, 372 20

In one embodiment, the invention relates to systems, methods and devices for improving the operation of an electromagnetic radiation source or component thereof. In one embodiment, the source is a laser source. A Fourier domain mode locked laser can be used in various embodiments. The sources described herein can be used in an optical coherence tomography (OCT) system such as a frequency domain OCT system. In one embodiment, laser coherence length is increased by compensating for dispersion. A frequency shifter can also be used in one embodiment to compensate for a tunable filter induced Doppler shift.

8582934, Nov 12, 2013

Apr 22, 2010

12/765501

Desmond Adler - Melrose MA, US
Stephen McCartin - Chelmsford MA, US
Christopher Petersen - Carlisle MA, US
Joseph Schmitt - Andover MA, US

Lightlab Imaging, Inc. - Westford MA

G02B 6/26
G01B 11/14

385 33, 385 39, 385 79, 356614

In part, the invention relates to optical caps having at least one lensed surface configured to redirect and focus light outside of the cap. The cap is placed over an optical fiber. Optical radiation travels through the fiber and interacts with the optical surface or optical surfaces of the cap, resulting in a beam that is either focused at a distance outside of the cap or substantially collimated. The optical elements such as the elongate caps described herein can be used with various data collection modalities such optical coherence tomography. In part, the invention relates to a lens assembly that includes a micro-lens; a beam director in optical communication with the micro-lens; and a substantially transparent film or cover. The substantially transparent film is capable of bi-directionally transmitting light, and generating a controlled amount of backscatter. The film can surround a portion of the beam director.

20100087741, Apr 8, 2010

Oct 2, 2009

12/572473

Alexandre Douplik - Erlangen, DE
Desmond C. Adler - Melrose MA, US
Brian C. Wilson - Toronto, CA
Norman Marcon - Toronto, CA

NOVADAQ TECHNOLOGIES INC. - Mississauga

A61B 6/00

600476

A method is described for computing a statistically significant difference between dysplasia and Barrett's esophagus (both with and without inflammatory component) using a discriminate function with diffuse reflectance measurements performed at a minimum of four different wavelengths of 485, 513, 598, and 629 nm. The discriminate function found depends both on local blood fraction volume Tand oxygenation SO. A pull-back approach of spectral data acquisition is disclosed which takes into account tissue motility in esophagus and measurement geometry peculiarities. The pull-back approach provides a significant improvement of measurement reproducibility and reduction of data deviation by 75-100%, resulting in a better discrimination between different histological groups.

20120250028, Oct 4, 2012

Mar 31, 2011

13/077075

Joseph M. Schmitt - Andover MA, US
Desmond Adler - Melrose MA, US

LIGHTLAB IMAGING, INC. - Westford MA

G02B 6/27
F21V 11/00
G01B 9/02
G02B 6/26
G02B 6/35

356492, 385 11, 385 27, 385 17, 362257

In one embodiment, the invention relates to an apparatus for increasing the repetition rate in a light source. The apparatus includes a first optical coupler comprising a first arm, a second arm and a third arm; a first mirror in optical communication with the second arm of the first optical coupler; and a first optical delay line having a first end in optical communication with the third arm of the first optical coupler and a second end in optical communication with a second mirror, wherein light entering the first arm of the first optical coupler leaves the first arm of the first optical coupler either delayed by an amount (τ) or substantially undelayed.

20120310081, Dec 6, 2012

May 31, 2012

13/484763

Desmond Adler - Melrose MA, US
Joseph M. Schmitt - Andover MA, US
Mattias Dahlberg - Uppsala, SE
Par Gustafsson - Uppsala, SE
Ulrik Hubinette - Alunda, SE
Magnus Samuelsson - Uppsala, SE
Johan Svanerudh - Uppsala, SE

LIGHTLAB IMAGING, INC. - Westford MA

A61B 5/0215
A61B 8/12
A61B 6/02

600427

In part, the invention relates to an image data collection system. The system can include an interferometer having a reference arm that includes a first optical fiber of length of L and a sample arm that includes a second optical fiber of length of L and a first rotary coupler configured to interface with an optical tomography imaging probe, wherein the rotary coupler is in optical communication with the sample arm. In one embodiment, L is greater than about 5 meters. The first optical fiber and the second optical fiber can both be disposed in a common protective sheath. In one embodiment, the system further includes an optical element configured to adjust the optical path length of the reference arm, wherein the optical element is in optical communication with the reference arm and wherein the optical element is transmissive or reflective.

20130058364, Mar 7, 2013

Oct 18, 2012

13/654878

MASSACHUSETTS INSTITUTE OF TECHNOLOG - Cambridge MA, US
James G. Fujimoto - Medford MA, US
Desmond C. Adler - Melrose MA, US

MASSACHUSETTS INSTITUTE OF TECHNOLOGY - Cambridge MA

H01S 3/098

372 18

A control system for improving and stabilizing Fourier domain mode locking (FDML) operation. The control system may also provide regulation of FDML operational parameters such as filter tuning, laser gain, polarization, polarization chromaticity, elliptical polarization retardance, and/or dispersion. The control system may be located internal to or external from the FDML laser cavity.

20130178748, Jul 11, 2013

Sep 24, 2012

13/625867

Alexandre Douplik - Erlangen, DE
Desmond C. Adler - Melrose MA, US
Brian C. Wilson - Toronto, CA
Norman Marcon - Toronto, CA

NOVADAQ TECHNOLOGIES INC. - Mississauga

A61B 5/00

600476

A method is described for computing a statistically significant difference between dysplasia and Barrett's esophagus (both with and without inflammatory component) using a discriminate function with diffuse reflectance measurements performed at a minimum of four different wavelengths of 485, 513, 598, and 629 nm. The discriminate function found depends both on local blood fraction volume Tand oxygenation SO. A pull-back approach of spectral data acquisition is disclosed which takes into account tissue motility in esophagus and measurement geometry peculiarities. The pull-back approach provides a significant improvement of measurement reproducibility and reduction of data deviation by 75-100%, resulting in a better discrimination between different histological groups.