US Patent:
20090280479, Nov 12, 2009
Inventors:
Dave S.B. Hoon - Santa Monica CA, US
Naoyuki Umetani - Tokyo, JP
Eiji Sunami - Los Angeles CA, US
Assignee:
JOHN WAYNE CANCER INSTITUTE - Santa Monica CA
International Classification:
C12Q 1/68
Abstract:
A method of detecting circulating DNA in a body fluid. The method comprises identifying a subject suffering from or at risk for developing cancer, obtaining a body fluid sample from the subject, and determining the sequence integrity of circulating DNA in the sample, wherein the circulating DNA is not purified from the sample.