Inventors:
Stephen Caltabiano - King of Prussia PA, US
Eliot Ohlstein - Glenmoore PA, US
Stewart McCallum - King of Prussia PA, US
Assignee:
Altherx, Inc. - Glenmoore PA
International Classification:
A01N 33/02
A61K 31/135
A01N 33/00
A61K 31/13
A61K 31/16
A01N 43/04
A61K 31/70
US Classification:
514646, 514579, 514 25, 514659
Abstract:
Pharmaceutical combinations comprising a beta-3 adrenergic receptor agonist and a muscarinic receptor antagonist, and methods for their use are disclosed. Disclosed combinations include solabegron and oxybutynin. Methods of using the pharmaceutical combinations for the treatment of one or more symptoms associated with overactive bladder, for example, frequency of urgency, nocturia, and urinary incontinence, are also disclosed.