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Erno M Keskeny

from Wilmington, DE
Age ~63

Erno Keskeny Phones & Addresses

  • 2 N Cliffe Dr, Wilmington, DE 19809 (302) 426-1351
  • 1021 Trenton Pl, Wilmington, DE 19801 (302) 322-6715 (302) 426-1351
  • 32 Aidone Dr, New Castle, DE 19720 (302) 322-6715
  • Newark, DE
  • North Providence, RI

Resumes

Resumes

Erno Keskeny Photo 1

Research Chemist At Johnson Matthey Pharmaceuticals And Glass Artist At Helikon Glass

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Position:
Senior Research Chemist at Johnson Matthey
Location:
Greater Philadelphia Area
Industry:
Pharmaceuticals
Work:
Johnson Matthey - West Deptford, NJ since Aug 2001
Senior Research Chemist

DuPont - Stine Haskell Research Center Sep 1994 - Jul 2001
Principal Scientist

Brown University Sep 1992 - Jul 1994
Postdoctoral Fellowship

University at Albany Aug 1990 - Sep 1992
Postdoctoral Fellowship

Gedeon Richter Jan 1985 - Jul 1990
Research Scientist
Education:
Budapest University of Technology and Economics 1990
Ph.D, Medicinal Chemistry; Economics
Budapest University of Technology and Economics 1985
M.Sc, Organic Chemistry
Budapest University of Technology and Economics 1980 - 1983
B.Sc, Organic Chemistry; Economics
Fleischer Art Memorial 2011 - 2012
Salem County Community College
UARTS
Interests:
Glass Art, Glass chemistry, Music, Science, Literature
Languages:
English, Hungarian, Russian, German
Erno Keskeny Photo 2

Senior Research Chemist At Johnson Matthey Pharmaceutical Materials

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Location:
Groraum Philadelphia und Umgebung
Industry:
Pharmazie
Erno Keskeny Photo 3

Erno Keskeny

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Location:
Greater Philadelphia Area
Industry:
Pharmaceuticals

Publications

Us Patents

Method For Making Analgesics

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US Patent:
7851482, Dec 14, 2010
Filed:
Oct 3, 2007
Appl. No.:
11/866840
Inventors:
Erno M. Keskeny - Wilmington DE, US
James J. Mencel - North Wales PA, US
Assignee:
Johnson Matthey Public Limited Compnay - London
International Classification:
A61K 31/485
C07D 489/04
US Classification:
514282, 546 45, 546 44
Abstract:
Improved analgesic oxymorphone hydrochloride contains less than 10 ppm of alpha, beta unsaturated ketones and pharmaceutical preparations comprising such oxymorphone hydrochloride. The oxymorphone hydrochloride is produced by reducing a starting material oxymorphone hydrochloride using gaseous hydrogen and under specified acidity, solvent system and temperature conditions. A specific polymorph of oxymorphone hydrochloride may be obtained by hydration.

Preparation Of Oxycodone

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US Patent:
20060111383, May 25, 2006
Filed:
Sep 23, 2005
Appl. No.:
11/234627
Inventors:
Michael Casner - Pitman NJ, US
Erno Keskeny - Wilmington DE, US
Jin Luo - Fullerton CA, US
International Classification:
C07D 489/02
A61K 31/485
US Classification:
514282000, 546045000
Abstract:
A process for preparing oxycodone or an oxycodone salt, wherein the oxycodone or oxycodone salt has low levels of impurities (especially 14-hydroxycodeinone) is disclosed. The process comprises the steps of: a) preparing a mixture comprising oxycodone and a solvent and adjusting the pH of the mixture to less than 6; and subsequently b) exposing the mixture to hydrogenation reagents for a period of at least 1 hour.

Preparation Of Oxycodone

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US Patent:
20070037982, Feb 15, 2007
Filed:
Oct 25, 2006
Appl. No.:
11/586392
Inventors:
Michael Casner - Pitman NJ, US
Erno Keskeny - Wilmington DE, US
Jin Luo - Fulletron CA, US
International Classification:
C07D 489/02
US Classification:
546045000
Abstract:
A method of purifying oxycodone or a salt thereof includes the steps of: a) preparing a solution including the oxycodone or salt thereof in a solvent, the solution having a pH less than 6, and; b) maintaining the solution at a temperature of at least 55 C. for a period of at least 1 hour; wherein the step of maintaining is performed in the absence of hydrogenation reagents.

Preparation Of Oxycodone

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US Patent:
20070219373, Sep 20, 2007
Filed:
May 23, 2007
Appl. No.:
11/752728
Inventors:
Michael Casner - Pitman NJ, US
Erno Keskeny - Wilmington DE, US
Jin Luo - Fullerton CA, US
Assignee:
JOHNSON MATTHEY PUBLIC LIMITED COMPANY - London
International Classification:
C07D 489/04
C07D 489/02
US Classification:
546045000
Abstract:
A process for preparing oxycodone or an oxycodone salt, wherein the oxycodone or oxycodone salt has low levels of impurities (especially 14-hydroxycodeinone) is disclosed. The process comprises the steps of: a) preparing a mixture comprising oxycodone and a solvent and adjusting the pH of the mixture to less than 6; and subsequently b) exposing the mixture to hydrogenation reagents for a period of at least 1 hour.

Preparation Of Oxycodone

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US Patent:
20070281958, Dec 6, 2007
Filed:
Aug 6, 2007
Appl. No.:
11/890397
Inventors:
Michael Casner - Pitman NJ, US
Erno Keskeny - Wilmington DE, US
Jin Luo - Fullerton CA, US
Assignee:
Johnson Matthey Public Limited Company - London
International Classification:
A61K 31/439
A61P 43/00
C07D 489/02
US Classification:
514282000, 546045000
Abstract:
A process for preparing oxycodone or an oxycodone salt, wherein the oxycodone or oxycodone salt has low levels of impurities (especially 14-hydroxycodeinone) is disclosed. The process comprises the steps of: a) preparing a mixture comprising oxycodone and a solvent and adjusting the pH of the mixture to less than 6; and subsequently b) exposing the mixture to hydrogenation reagents for a period of at least 1 hour. This process provides oxycodone with very low levels of α,β-unsaturated ketone impurities. Oxycodone or an oxycodone salt produced according to the process of the invention has low levels of α,β-unsaturated ketones and is advantageously incorporated into pharmaceutical products.

Preparation Of Oxycodone

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US Patent:
20080306265, Dec 11, 2008
Filed:
Aug 15, 2008
Appl. No.:
12/192632
Inventors:
Michael Lawrence Casner - Pitman NJ, US
Erno M. Keskeny - Wilmington DE, US
Jin Luo - Fullerton CA, US
Assignee:
Johnson Matthey Public Limited Company - London
International Classification:
C07D 489/00
US Classification:
546 45
Abstract:
A method of purifying oxycodone or a salt thereof includes the steps of:

Low Abuk Oxycodone, Its Salts And Methods Of Making Same

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US Patent:
20120259118, Oct 11, 2012
Filed:
Jul 1, 2011
Appl. No.:
13/175537
Inventors:
Erno M. Keskeny - Wilmington DE, US
James J. Mencel - North Wales PA, US
Assignee:
JOHNSON MATTHEY PUBLIC LIMITED COMPANY - London
International Classification:
C07D 489/08
US Classification:
546 45
Abstract:
A method of preparing oxycodone includes forming 14-hydroxycodeine by reduction of 14-hydroxycodeinone and rearrangement of the 14-hydroxycodeine to form the oxycodone. During the reduction step, the ketone group of an undesirable contaminant precursor, 8,14-dihydroxy-7,8-dihydrocodeinone, is reduced to a hydroxyl group thus forming a triol. This triol is substantially inert with respect to reforming 14-hydroxycodeinone and can be readily separated from oxycodone.
Erno M Keskeny from Wilmington, DE, age ~63 Get Report