Inventors:
Michael I. Lerman - Rockville MD
Farida Latif - Frederick MD
Berton Zbar - Garrett Park MD
Marston Linehan - Rockville MD
Assignee:
The United States of America as represented by the Department of Health
and Human Services - Washington DC
International Classification:
G01N 33574
G01N 3353
A61K 3800
C07K 500
Abstract:
The invention is the Von Hippel-Lindau (VHL) disease gene and its corresponding cDNA protein product, and antibodies therefore. Methods for detecting carriers of the VHL disease gene using probes derived from the cDNAs are described. Antibodies and methods of detecting the Von-Hippel-Lindau protein are also described.