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Gerard R Kieczykowski

from Westfield, NJ
Age ~74
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Also known as:
Gerard Dr Kieczykowski, Gerard L Kieczykowski, Gerard Kieczykowski Dr, Grard Kieczykowski, Martha L Kieczykowski, Martha Q Kieczykowski, I I, Gerard I, Ge Kieczykowski, Kieczykowski Ge
Phone and address:
248 Dudley Ave, Westfield, NJ 07090
(908) 654-9057
Related to:
Jean KieczykowskiLinda Oliver, 55Aubrey Cashion, 47Jeremy M Hebbel, 41Michael SchreiberLoic O Kreitmann, 52
Connected to:
Andrzej Kieda, 51Jennifer L Kieda, 36Johnson Kieda, 42Alex F Kiedaisch, 36Morgan T Kiedeisch, 32Mary L Kiederer, 86Patricia L Kiedinger, 68Katrina E Kiedis, 42Dianne E Kiedrowski, 57Kathlyn A Kiedrowski, 58

Gerard Kieczykowski Phones & Addresses

  • 248 Dudley Ave, Westfield, NJ 07090 (908) 654-9057 (908) 889-0149
  • Cranford, NJ
  • 65 Embury Ave, Ocean Grove, NJ 07756
  • 248 W Dudley Ave, Westfield, NJ 07090 (908) 313-9347

Work

Position: Administrative Support Occupations, Including Clerical Occupations

Publications

Us Patents

Process For Preparing 4-Amino-1-Hydroxybutylidene-1,1-Bisphosphonic Acid (Abp) Or Salts Thereof

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US Patent:
50196510, May 28, 1991
Filed:
Jun 20, 1990
Appl. No.:
7/540997
Inventors:
Gerard R. Kieczykowski - Westfield NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C07F 938
US Classification:
562 13
Abstract:
An improved process is described for the preparation of 4-amino-1-hydroxybutylidene-1,1-bisophosphonic acid (ABP) or salts thereof which comprises: (a) reacting 4-aminobutyric acid with a mixture of phosphorous acid and PCl. sub. 3 in the presence of methanesulfonic acid; (b) contacting the mixture from Step (a) with an aqueous hydrolysis mixture, wherein the pH is maintained in the range of 4 to 10 during the contacting; and (c) recovering said 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid or salts thereof.

Phenoxyphenylacetic Acid Derivatives

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US Patent:
56681763, Sep 16, 1997
Filed:
Oct 18, 1996
Appl. No.:
8/733536
Inventors:
Scott W. Bagley - Groton CT
Theodore P. Broten - Ambler PA
Prasun K. Chakravarty - Edison NJ
Daljit S. Dhanoa - Secaucus NJ
Kenneth J. Fitch - Cranford NJ
William J. Greenlee - Teaneck NJ
Nancy Jo Kevin - Clifton NJ
Gerard R. Kieczykowski - Westfield NJ
Douglas J. Pettibone - Chalfont PA
James R. Tata - Westfield NJ
Ralph A. Rivero - Tinton Falls NJ
Thomas F. Walsh - Westfield NJ
David L. Williams - Telford PA
Jay M. Matthews - Fords NJ
Richard B. Toupence - Cranford NJ
Assignee:
Merck & Co. Inc. - Rahway NJ
International Classification:
A61K 3119
A61K 31535
C07D26530
C07C 5911
US Classification:
514569
Abstract:
Phenoxyphenylacetic acids and derivatives of the general structural formula I ##STR1## have endothelin antagonist activity and are useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, endotoxic shock, benign prostatic hyperplasia, inflammatory diseases including Raynaud's disease and asthma.

Process For Preparing 4-Amino-1-Hydroxybutylidene-1,1-Bisphosphonic Acid Or Salts Thereof

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US Patent:
49220071, May 1, 1990
Filed:
Jun 9, 1989
Appl. No.:
7/363820
Inventors:
Gerard R. Kieczykowski - Westfield NJ
David G. Melillo - Scotch Plains NJ
Ronald B. Jobson - East Brunswick NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C07F 938
US Classification:
562 13
Abstract:
A process for the preparation of 4-amino-1-hydroxybutylidene-1, 1-bisphosphonic acid or salts thereof which comprises: (a) reacting 4-aminobutyric acid with a mixture of phosphorous acid and PC1. sub. 3 in the presence of methanesulfonic acid; and (b) recovering said 4-amino-1-hydroxybutylidene-1, 1-bisphosphonic acid or salts thereof.

Diphosphonate Intermediate For Preparing An Antihypercalcemic Agent

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US Patent:
50398199, Aug 13, 1991
Filed:
Sep 18, 1990
Appl. No.:
7/584322
Inventors:
Gerard R. Kieczykowski - Westfield NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C07F 940
US Classification:
548415
Abstract:
Described is a new diphosphonate intermediate useful in a new process for producing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid (ABP), a new antihypercalcemic agent. The process involves a 3-step sequence starting with 4-phthalimidobutanoyl chloride which can be practiced as a "one-pot" reaction sequence, without employing PCl. sub. 3 or H. sub. 3 PO. sub. 3. The new intermediate has the structure: ##STR1## where n=1-5.

Aryl And Heteroaryl Macrolides Having Immunosuppressive Activity

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US Patent:
55457347, Aug 13, 1996
Filed:
Oct 25, 1994
Appl. No.:
8/328225
Inventors:
Robert K. Baker - Cranford NJ
Gerard R. Kieczykowski - Westfield NJ
Hyun O. Ok - Edison NJ
William H. Parsons - Edison NJ
Kathleen M. Rupprecht - Cranford NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C07D49816
US Classification:
540456
Abstract:
Aryl and heteroaryl macrolides of the general structural Formula I: ##STR1## have been prepared from suitable precursors by olefination at C-27. These macrolide immunosuppressants are useful in a mammalian host for the treatment of autoimmune diseases, infectious diseases, the prevention of rejection of foreign organ transplants and/or related afflictions, diseases, and illnesses.

Process For Preparing An Antihypercalcemic Agent

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US Patent:
51591081, Oct 27, 1992
Filed:
Aug 1, 1991
Appl. No.:
7/742142
Inventors:
Gerard R. Kieczykowski - Westfield NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C07F 938
US Classification:
562 13
Abstract:
Described is a new process for producing 4-amino-1-hydroxybutylidene-1,1-bisphosphonic acid (ABP), a new antihypercalcemic agent. The process involves a 3-step sequence starting with 4-phthalimidobutanoyl chloride which can be practiced as a "one-pot" reaction sequence, without employing PCl. sub. 3 or H. sub. 3 PO. sub. 3.

Process For Producing N-Amino-1-Hydroxy-Alkylidene-1,1-Bisphosphonic Acids

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US Patent:
55105173, Apr 23, 1996
Filed:
Aug 4, 1994
Appl. No.:
8/286151
Inventors:
Richard R. Dauer - Longmont CO
Lisa DiMichele - North Plainfield NJ
Mauricio Futran - Westfield NJ
Gerard R. Kieczykowski - Westfield NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C07F 928
US Classification:
562 13
Abstract:
A process for continuously producing alkylpyrophosphonate, alkylpyrophosphate and multimers thereof and for producing 4-amino-1-hydroxyalkylidene-1,1-bisphosphonic acids or salts thereof.

Process For Producing N-Amino-1-Hydroxy-Alkyl-Idene-1,1-Bisphosphonic Acids

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US Patent:
56484917, Jul 15, 1997
Filed:
May 20, 1996
Appl. No.:
8/617851
Inventors:
Richard R. Dauer - Longmont CO
Lisa DiMichele - North Plainfield NJ
Mauricio Futran - Westfield NJ
Gerard R. Kieczykowski - Westfield NJ
Assignee:
Merck & Co., Inc. - Rahway NJ
International Classification:
C07D40506
US Classification:
546 22
Abstract:
A process for continuously producing alkylpyrophosphonate, alkylpyrophosphate and multimers thereof and for producing 4-amino-1-hydroxyalkylidene-1,1-bisphosphonic acids or salts thereof.
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Gerard R Kieczykowski from Westfield, NJ, age ~74 Get Report