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Herman O Sintim

from Westfield, IN
Age ~49
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Also known as:
Herman Sinto, Hermen Sintin, Herman M
Related to:
Tamia Smith, 25Henry Sintim, 53Sintim O Solace, 51Esther Sintim, 43
Connected to:
Darryl K Sintim-Aboagye, 40Charlene V Sintkowski, 51Brittney L Sintobin, 34Frances M Sinton, 67Joseph W Sinton, 66Krystle E Sinton, 39Jyri K Sintonen, 61Claire C Sintoni, 72Deidre M Sintoni, 54Marcus X Sintoni, 45

Herman Sintim Phones & Addresses

  • Westfield, IN
  • West Lafayette, IN
  • 2808 Federal Ln, Bowie, MD 20715
  • 1816 Greenwich Wood Dr #32, Silver Spring, MD 20903
  • 4408 West St, Hyattsville, MD 20782 (301) 277-3605
  • Palo Alto, CA
  • W Lafayette, IN

Work

Position: Professional/Technical

Education

Degree: Associate degree or higher

Public records

Vehicle Records

Herman Sintim

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Address:
1816 Greenwich Wood Dr APT 32, Silver Spring, MD 20903
Phone:
(301) 277-3605
VIN:
JTKDE167170145290
Make:
SCION
Model:
TC
Year:
2007

Resumes

Resumes

Herman Sintim Photo 1

Co-Founder

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Location:
1040 south River Rd, West Lafayette, IN 47906
Industry:
Higher Education
Work:
University of Maryland since Jul 2006
Associate Professor
Education:
Stanford University 2004 - 2006
University of Oxford 1999 - 2002
DPhil, organic chemistry University College London, U. of London 1995 - 1999
BSc, Medicinal Chemistry
Skills:
Organic Synthesis
Nmr
Organic Chemistry
Chemistry
Spectroscopy
Uv/Vis
Hplc
Lc Ms
Mass Spectrometry
Research
Biochemistry
Drug Design
Molecular Biology
Cancer
Microbiology
Organometallic Chemistry
Microsoft Office
Science
Interests:
Microbiology
Cancer
Chemical Biology
Herman Sintim Photo 2

Herman Sintim

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Publications

Us Patents

Phosphorylated And Branched Dihydroxy-Pentane-Dione (Dpd) Analogs As Quorum Sensing Inhibitors In Bacteria

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US Patent:
20120294900, Nov 22, 2012
Filed:
Mar 26, 2012
Appl. No.:
13/430000
Inventors:
Herman Sintim - Bowie MD, US
William E. Bentley - Annapolis MD, US
Varnika Roy - Bethesda MD, US
Jacqueline Smith - Bowie MD, US
Assignee:
UNIVERSITY OF MARYLAND, COLLEGE PARK - College Park MD
International Classification:
A01N 35/02
C07C 49/337
C07C 49/82
C07C 205/45
C07D 307/46
C07C 69/28
C07C 69/16
C07C 235/80
C07F 9/09
A61K 31/121
A01N 35/00
A01N 35/04
A61K 31/12
A01N 43/08
A61K 31/341
A01N 37/12
A01N 57/12
A61K 31/661
A01P 1/00
A61P 31/04
A61K 9/00
C07C 49/17
US Classification:
424400, 568413, 568303, 568381, 568336, 568306, 549488, 560264, 564199, 558178, 568379, 514675, 514690, 514689, 514676, 514461, 514547, 514125
Abstract:
Provided are compositions and methods for modulating quorum sensing in microbes. The compounds are AI-2 analogs and as such have structures similar to 4,5-dihydroxy-2,3-pentanedione that can act as agonists/antagonists of quorum sensing. The compounds are useful for modulating quorum sensing in bacteria and can be used in methods for prophylaxis or therapy of bacterial infections and for reduction of biofilms.

Probes And Methods For Detecting Analytes

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US Patent:
20110207132, Aug 25, 2011
Filed:
Aug 4, 2009
Appl. No.:
13/057417
Inventors:
Herman Sintim - Silver Spring MD, US
Assignee:
UNIVERSITY OF MARYLAND - College Park MD
International Classification:
C12Q 1/68
C07H 21/00
US Classification:
435 611, 536 243
Abstract:
Embodiments disclosed herein relate generally to probes, methods, and kits for detecting the presence of a target analyte. The probe generally comprises two strands that have regions of complementarity and do not associate with each other at the reaction temperature. In the presence of an analyte, the two strands of the probe can hybridize to each other, and the analyte can hybridize to both strands of the probe in a juxtapose manner to form a tripartite structure (probe-analyte complex). If the region of complementarity between the two probe strands contain cognate restriction endonuclease (REN) sequences, then the formation of the tripartite structure will lead to the generation of a REN site that can be cleaved by a REN, and the cleavage can then be detected by a variety of methods to signal the presence of the analyte.

Dock Derived Compound Against Laminin Receptor (37 Lr) And Uses Thereof

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US Patent:
20200064334, Feb 27, 2020
Filed:
Aug 29, 2019
Appl. No.:
16/555486
Inventors:
- West Lafayette IN, US
Charles Samuel Umbaugh - Heidelberg, DE
Herman O. Sintim - West Lafayette IN, US
Adriana Diaz-Quinones - West Lafayette IN, US
Assignee:
Purdue Research Foundation - West Lafayette IN
International Classification:
G01N 33/50
G01N 33/574
A61K 31/497
G16C 20/60
G16C 20/50
G16B 15/30
Abstract:
An in silico screening method generated compounds that are against laminin receptor 37LR and their anti-cancer functions in prostate cancer cell lines are disclosed herein. A group of derivatives based on the hit compound from the in silico screening are synthesized and tested with improved ICvalue that can have relevant clinical use for prostate cancer or osteoarthritis.

4-Substituted Aminoisoquinoline Derivatives

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US Patent:
20190177278, Jun 13, 2019
Filed:
Aug 15, 2017
Appl. No.:
16/325022
Inventors:
- West Lafayette IN, US
Herman O. SINTIM - West Lafayette IN, US
Assignee:
Purdue Research Foundation - West Lafayette IN
International Classification:
C07D 217/22
C07D 471/04
C07D 233/10
C07D 413/06
C07D 401/06
C07D 209/49
C07D 221/02
C07D 271/06
A61P 35/00
Abstract:
This invention relates to 4-substituted isoquinoline compounds and their derivatives and uses thereof for treatment of cancer, for example, acute myeloid leukemia.

Dock Derived Compound Against Laminin Receptor (37 Lr) And Uses Thereof

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US Patent:
20190065669, Feb 28, 2019
Filed:
Aug 27, 2018
Appl. No.:
16/113718
Inventors:
- West Lafayette IN, US
Charles Samuel Umbaugh - Heidelberg, DE
Herman O. Sintim - West Lafayette IN, US
Adriana Diaz-Quinones - West Lafayette IN, US
Assignee:
Purdue Research Foundation - West Lafayette IN
International Classification:
G06F 19/16
C40B 30/02
A61K 31/497
A61P 35/00
A61P 19/02
Abstract:
An in silico screening method generated compounds that are against laminin receptor 37 LR and their anti-cancer functions in prostate cancer cell lines are disclosed herein. A group of derivatives based on the hit compound from the in silico screening are synthesized and tested with improved ICvalue that can have relevant clinical use for prostate cancer or osteoarthritis.
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Herman O Sintim from Westfield, IN, age ~49 Get Report