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Hugues J Ryser

from Concord, MA
Age ~98
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Also known as:
Hugues Dr Ryser, Hugues D Ryser, Hughes Jp Ryser, Hugues J Pryser, Hughes J Ryser, Jp Ryser Hughes, Y Ryser Hugues, Ryser Hugues
Phone and address:
503 Annursnac Hill Rd, West Concord, MA 01742
(978) 369-6059
Related to:
Christopher M Davis, 56
Connected to:
Bruce W Ryser, 73Cameron J Ryser, 28Christopher E Ryser, 55Craig A Ryser, 39Delilah M Ryser, 56Dustin M Ryser, 42Jean L Ryser, 76Rosemary Ryser, 95Cindy L Rysewyk, 74Phillip A Rysewyk, 46

Hugues Ryser Phones & Addresses

  • 503 Annursnac Hill Rd, Concord, MA 01742 (978) 369-6059
  • Boston, MA

Work

Company: Boston university Position: Emeritus professor of pathhology

Industries

Higher Education

Resumes

Resumes

Hugues Ryser Photo 1

Emeritus Professor Of Pathhology

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Location:
Boston, MA
Industry:
Higher Education
Work:
Boston University
Emeritus Professor of Pathhology

Business Records

Name / Title
Company / Classification
Phones & Addresses
Hugues Ryser
Principal
Ryser Hugues Dr
Medical Doctor's Office
503 Annursnac Hl Rd, West Concord, MA 01742

Publications

Us Patents

Acidity-Sensitive Spacer Molecule To Control The Release Of Pharmaceuticals From Molecular Carriers

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US Patent:
46311904, Dec 23, 1986
Filed:
Jun 26, 1981
Appl. No.:
6/277633
Inventors:
Wei C. Shen - Needham MA
Hugues J. Ryser - Concord MA
International Classification:
A61K 3944
US Classification:
424 85
Abstract:
A method for controlling the release of drugs or other passenger moleculars from carrier conjugates, and a class of conjugates that releases drugs when ingested by a cell or subjected to acidic conditions, are disclosed. These conjugates contain a passenger molecule which is attached to a spacer molecule through an acidic bonding group, such as carboxyl, that is in a "cis" configuration with another acidic group, and a carrier molecule that is bonded to the spacer molecule at another site. When subjected to a mile increase in acidity, such as occurs within a lysosome of a cell, the drug or other passenger molecule is hydrolyzed from the conjugate and released in unmodified, active form.

Acidity-Sensitive Spacer Molecule To Control The Release Of Pharmaceuticals From Molecular Carriers

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US Patent:
51440113, Sep 1, 1992
Filed:
Feb 6, 1989
Appl. No.:
7/308960
Inventors:
Wei C. Shen - Needham MA
Hugues J.-P. Ryser - Concord MA
Assignee:
Boston University - Boston MA
International Classification:
C07K 1706
A61K 3944
A61K 4748
US Classification:
5303915
Abstract:
A method for controlling the release of durgs or other passenger molecules form carrier conjugates, and a class of conjugates that releases drugs when ingested by a cell or subjected to acidic conditions, are disclosed. These conjugates contain a passenger molecule which is attached to a spacer molecule through an acidic bonding group, such as carboxyl, that is in a "cis" configuration with another acidic group, and a carrier molecule that is bonded to the spacer molecule at another site. When subjected to a mild increase in acidity, such as occurs within a lysosome of a cell, the drug or other passenger molecule is hydrolyzed from the the conjugate and released in unmodified, active form.

Method Of Effecting Cellular Uptake Of Molecules

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US Patent:
47015217, Oct 20, 1987
Filed:
Jan 10, 1979
Appl. No.:
6/002368
Inventors:
Hugues J. Ryser - Concord MA
Wei-Chiang Shen - Needham MA
Assignee:
The Trustees of Boston University - Boston MA
International Classification:
C07K 900
US Classification:
530322
Abstract:
A method of effecting cellular uptake of molecules which are either excluded from cells or poorly transported into cells is disclosed wherein such molecules are covalently bonded to a cationic polymer which serves as a transport carrier to transport the molecules into cells.
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Hugues J Ryser from Concord, MA, age ~98 Get Report