Inventors:
Lisa A. Alex - Pasadena CA
Melvin I. Simon - San Marino CA
Claude Selitrennikoff - Evergreen CO
Jacqueline Agnan - Aurora CO
Assignee:
University Technology Corporation - CO
California Institute of Technology - CA
International Classification:
C12N 121
Abstract:
The present invention relates to histidine kinases, including osmosensing fungal histidine kinases. In particular, the present invention provides amino acid and nucleic acid sequences of fungal histidine kinases from organisms such as Candida (e. g. , C. albicans) and Neurospora (e. g. , N. crassa). The present invention further provides compositions and methods for the development of antifungal compounds.