James E Usowicz

7951597, May 31, 2011

Sep 15, 2006

11/532234

James E. Usowicz - Webster MA, US
Theodore C. Ciolkosz - Milton MA, US
Russell Keene - Sudbury MA, US
Daniel J. McCormick - Westford MA, US

Waters Technologies Corporation - Milford MA

G01N 1/10
G01N 35/10

436 43, 73 6156, 73 6456, 7386383, 7386421, 7386483, 422 67, 422501, 422522, 422546, 422 70, 436 54, 436161, 436180

The present invention is a pressurized fluid sample injector system consisting of a sample needle, multiport valve, sample loop, metering syringe and a pressure assist pump. The speed of sample transport into the sample loop is increased by pressurizing the fluid in the system and metering the sample into the sample loop. The elevated system pressure allows the fluids to be moved faster than the vapor pressure would normally allow in a system at ambient pressure.

8047060, Nov 1, 2011

Jan 31, 2006

11/814574

Theodore A. Dourdeville - Marion MA, US
Russell L. Keene - Sudbury MA, US
Theodore D. Ciolkosz - Milton MA, US
James E. Usowicz - Webster MA, US

Waters Technologies Corporation - Milford MA

G01N 1/00
G01N 30/00

73 6156, 137250, 251304

The present invention provides a method and apparatus for substantially eliminating destructive transients of pressure or flow rate which can degrade the efficiency and useful lifetime of chromatography columns. The present invention enables a substantially constant flow of mobile phase liquid to be maintained through the chromatography system by eliminating the flow blockage interval associated with the actuation of sample injection valves. The present invention further provides a method to reduce the pressure and flow rate transients associated with pressurization of the sample loop contents when the sample loop is introduced to chromatography system delivery pressure.

8151629, Apr 10, 2012

Mar 2, 2005

10/598075

Theodore D. Ciolkosz - Milton MA, US
James E. Usowicz - Webster MA, US
Peyton C. Beals - Wrentham MA, US
Russell Keene - Sudbury MA, US

Waters Technologies Corporation - Milford MA

G01M 3/04

73 40, 210741

A device comprising a pressure monitor and a control means that receives a signal representing measured pressure at the pressure monitor and controls the controllable elements of a fluid system is utilized to monitor a fluid system for error conditions, to optimize operations and to diagnose the fluid system. By following a testing protocol that selectively enables parts of the system, the control means narrows the list of possible failing components. Comparing the measured pressure against normal pressures allows the device to identify error conditions. Determining the volume of fluid being transported and controlling the duration of the flow optimizes operation of the fluid system.

8281812, Oct 9, 2012

Mar 2, 2005

10/598316

James E. Usowicz - Webster MA, US
Theodore C. Ciolkosz - Milton MA, US
Marc Lemelin - Whitinsville MA, US

Waters Technologies Corporation - Milford MA

F16K 11/074

13762515, 251208, 251304, 251368

Embodiments of the present invention feature a method and device for controlling the flow of fluid. One embodiment of the device for controlling the flow of fluid comprises a rotor, stator and compression means. The rotor has a rotor fluid communication means and at least one rotor load bearing surface. The rotor load bearing surface sealably engages a stationary load bearing surface. The rotor is capable of assuming a first position and a second position by rotation. The stator has a stationary load bearing surface having stator fluid communication means. The stationary load bearing surface sealably engages the rotor load bearing surface and permits rotation of the rotor with respect to the stator. At least one of the rotor bearing surface and said stator load bearing surface has a diamond-like carbon-silica coating.

8312762, Nov 20, 2012

Mar 16, 2007

12/282895

Keith Fadgen - Hope Valley RI, US
James E. Usowicz - Webster MA, US
Miguel Soares - Norton MA, US

Waters Technologies Corporation - Milford MA

G01M 30/02

73 6155, 73 6156

Embodiments of the present invention are directed to methods and apparatus for placing a sample in a chromatographic system. The device and method feature placing samples held in a sample loop to pressurization prior to placing such sample loop in communication with high pressure conduits.

8539819, Sep 24, 2013

Mar 9, 2012

13/416364

Theodore D. Ciolkosz - Plymouth MA, US
James E. Usowicz - Webster MA, US
Peyton C. Beals - Wrentham MA, US
Russell Keene - Sudbury MA, US

Waters Technologies Corporation - Milford MA

G01M 3/04

73 40, 210741

A device comprising a pressure monitor and a control means that receives a signal representing measured pressure at the pressure monitor and controls the controllable elements of a fluid system is utilized to monitor a fluid system for error conditions, to optimize operations and to diagnose the fluid system. By following a testing protocol that selectively enables parts of the system, the control means narrows the list of possible failing components. Comparing the measured pressure against normal pressures allows the device to identify error conditions. Determining the volume of fluid being transported and controlling the duration of the flow optimizes operation of the fluid system.

20050194298, Sep 8, 2005

Mar 4, 2005

11/072906

James Usowicz - Douglas MA, US
Theodore Ciolkosz - Milton MA, US
Russell Keene - Sudbury MA, US
Daniel McCormick - Westford MA, US

WATERS INVESTEMENTS LIMITED - New Castle DE

B01D015/08

210098000, 210659000, 073061550, 422063000, 210198200

The present invention is a pressurized fluid sample injector system consisting of a sample needle, multiport valve, sample loop, metering syringe and a pressure source. The method and apparatus of the present invention provides increased speed of sample transport into the sample loop by pressurizing the fluid in the system and metering the sample into the sample loop. The elevated system pressure allows the fluids to be moved faster than the vapor pressure would normally allow in a system at ambient pressure.

20070287192, Dec 13, 2007

Mar 2, 2005

10/598071

James Usowicz - Webster MA, US
Peyton Beals - Wrentham MA, US
Russell Keene - Sudbury MA, US
Richard Kent - Norfolk MA, US
Miguel Soares - Norton MA, US
John Heden - Hollis NH, US

Waters Investments Limited - New Castle DE

G01N 30/02
B01J 19/00
G01N 30/62
G01N 1/28

436161000, 422070000, 073053010, 073064560

A device () for detecting a condition in a fluid system () and initiating a response based on the condition. The device consists of a sensor () that responds to a first and second condition of the fluid () in the system and a control means () that receives the responses and generates command signals in based on the received response. In a liquid chromatography system, the device is used to determine the volume of components of the fluid system. In addition, the device allow leaks to be detected and permits the fluid in the system to be transported at a optimum speed. The device is well implemented utilizing to a light emitter and light receptor that are sensitive to the fluid in either a gaseous or liquid state.