Search

Miguel Suastegui Phones & Addresses

  • Boston, MA
  • Ames, IA

Publications

Us Patents

Methods And Compositions For Production Of Aromatic And Other Compounds In Yeast

View page
US Patent:
20210040490, Feb 11, 2021
Filed:
Jul 28, 2020
Appl. No.:
16/947304
Inventors:
- Ames IA, US
Mingfeng Cao - Ames IA, US
Miguel Suastegui - Ames IA, US
Meirong Gao - Ames IA, US
International Classification:
C12N 15/81
C12N 9/10
C12N 9/02
C12P 5/00
C12N 9/88
C12N 15/10
C12P 7/44
C12P 7/42
Abstract:
The present disclosure includes methods and components for production of valuable industrial compounds in yeast. In an embodiment, the present invention provides a nucleic acid construct with increased stability for gene expression or gene editing comprising: a nucleic acid sequence encoding one or more of SEQ ID NO: 1-8 (CENs 1-8); and one or more regulatory elements functional in a yeast cell. In an embodiment of the present invention the nucleic acid constructs are vectors, preferably episomal vectors. High expression promoters, as well as methods for increasing production of compounds such as aromatics are disclosed.

Methods And Compositions For Production Of Aromatic And Other Compounds In Yeast

View page
US Patent:
20190002892, Jan 3, 2019
Filed:
Jun 27, 2018
Appl. No.:
16/019822
Inventors:
- Ames IA, US
Mingfeng Cao - Ames IA, US
Miguel Suastegui - Ames IA, US
Meirong Gao - Ames IA, US
International Classification:
C12N 15/81
C12N 9/10
C12N 9/02
C12N 9/88
C12P 5/00
Abstract:
The present disclosure includes methods and components for production of valuable industrial compounds in yeast. In an embodiment, the present invention provides a nucleic acid construct with increased stability for gene expression or gene editing comprising: a nucleic acid sequence encoding one or more of SEQ ID NO: 1-8 (CENs 1-8); and one or more regulatory elements functional in a yeast cell. In an embodiment of the present invention the nucleic acid constructs are vectors, preferably episomal vectors. High expression promoters, as well as methods for increasing production of compounds such as aromatics are disclosed.
Miguel Suastegui from Boston, MA Get Report