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Laykea Tafesse Phones & Addresses

  • Trenton, NJ
  • Tallahassee, FL
  • Arlington, VA
  • Washington, DC
  • Springfield, VA
  • Plainsboro, NJ
  • Silver Spring, MD

Publications

Us Patents

Therapeutic Agents Useful For Treating Pain

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US Patent:
7799786, Sep 21, 2010
Filed:
Sep 4, 2007
Appl. No.:
11/899379
Inventors:
Donald J. Kyle - Newtown PA, US
Qun Sun - Princeton NJ, US
Laykea Tafesse - Robbinsville NJ, US
Chongwu Zhang - Dayton NJ, US
Xiaoming Zhou - Plainsboro NJ, US
Assignee:
Purdue Pharma L.P. - Stamford CT
International Classification:
C07D 237/00
C07D 241/00
A61K 31/50
A61K 31/497
US Classification:
51425201, 5142521, 544224, 544336
Abstract:
A compound of formula:.

Therapeutic Agents Useful For Treating Pain

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US Patent:
8008300, Aug 30, 2011
Filed:
Jul 8, 2009
Appl. No.:
12/499480
Inventors:
Qun Sun - Princeton NJ, US
Laykea Tafesse - Robbinsville NJ, US
Sam Victory - Oak Ridge NC, US
Assignee:
Purdue Pharma L.P. - Stamford CT
International Classification:
A61K 31/50
A61K 31/497
C07D 403/04
C07D 241/02
US Classification:
51425202, 51425404, 51425406, 544238, 544357, 544368, 544370
Abstract:
A compound of formula:.

Fused And Spirocycle Compounds And The Use Thereof

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US Patent:
8193208, Jun 5, 2012
Filed:
Sep 8, 2006
Appl. No.:
11/991626
Inventors:
Zhengming Chen - Belle Mead NJ, US
Laykea Tafesse - Robbinsville NJ, US
Jiangchao Yao - Monmouth Junction NJ, US
Khondaker Islam - Mystic CT, US
Assignee:
Purdue Pharma L.P. - Stamford CT
International Classification:
A61K 31/438
C07D 491/107
US Classification:
514278, 546 17
Abstract:
The invention relates to fused and spirocycle compounds of Formula I:.

Tetrahydropyridinyl And Dihydropyrrolyl Compounds And The Use Thereof

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US Patent:
8324249, Dec 4, 2012
Filed:
Aug 3, 2009
Appl. No.:
13/056839
Inventors:
Hidenori Mikamiyama - Osaka, JP
Chiyou Ni - Belle Mead NJ, US
Bin Shao - Richboro PA, US
Laykea Tafesse - Robbinsville NJ, US
Assignee:
Purdue Pharma L.P. - Stamford CT
Shionogi & Co., Ltd. - Osaka
International Classification:
A01N 43/40
A61K 31/445
US Classification:
514318, 514326, 544192, 544193, 544208, 544209, 544210, 544211
Abstract:
The invention relates to tetrahydropyridinyl and dihydropyrrolyl compounds of Formula (I): and pharmaceutically acceptable salts, prodrugs, or solvates thereof, wherein X, Y, Z, R, R, m, and n are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula (I) to treat a disorder responsive to the blockade of calcium channels, and particularly N-type calcium channels. Compounds of the present invention are especially useful for treating pain.

Substituted Pyridines Useful For Treating Pain

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US Patent:
8389549, Mar 5, 2013
Filed:
Apr 25, 2008
Appl. No.:
12/596997
Inventors:
Laykea Tafesse - Robbinsville NJ, US
Assignee:
Purdue Pharma L.P. - Stamford CT
International Classification:
A61K 31/44
US Classification:
514340, 5462681
Abstract:
A compound of Formula: (I) or a pharmaceutically acceptable derivative thereof, where Ar, Ar, X, R, and m are as disclosed herein. Compounds of Formulae (I)-(V) and pharmaceutically acceptable derivatives thereof; compositions comprising an effective amount of a compound of Formulae (I)-(V) or a pharmaceutically acceptable derivative thereof; and methods for treating or preventing pain, UI, an ulcer, IBD, or IBS in an animal comprising administering to an animal in need thereof an effective amount of a compound of Formulae (I)-(V) or a pharmaceutically acceptable derivative thereof are disclosed herein.

Trpv1 Antagonists Including Dihydroxy Substituent And Uses Thereof

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US Patent:
8476277, Jul 2, 2013
Filed:
Apr 25, 2008
Appl. No.:
12/110155
Inventors:
Laykea Tafesse - Robbinsville NJ, US
Assignee:
Purdue Pharma L.P. - Stamford CT
International Classification:
A61K 31/444
A61K 31/4545
A61K 31/496
A61P 1/00
C07D 401/04
C07D 401/14
C07D 417/04
US Classification:
5142531, 51425301, 514318, 514334, 544360, 544364, 546194, 546257, 546258
Abstract:
The invention relates to compounds of formula IA.

Therapeutic Agents Useful For Treating Pain

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US Patent:
8536177, Sep 17, 2013
Filed:
Aug 8, 2011
Appl. No.:
13/205323
Inventors:
Qun Sun - Princeton NJ, US
Laykea Tafesse - Robbinsville NJ, US
Sam Victory - Oak Ridge NC, US
Assignee:
Purdue Pharma L.P. - Stamford CT
International Classification:
A61K 31/497
A61K 31/435
C07D 279/10
C07D 401/14
US Classification:
51425203, 5142531, 514277, 544 586, 544238, 544364
Abstract:
A compound of formula:.

Heterocyclic Trpv1 Receptor Ligands

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US Patent:
8546388, Oct 1, 2013
Filed:
Oct 22, 2009
Appl. No.:
12/603733
Inventors:
Donald J. Kyle - Yardley PA, US
Laykea Tafesse - Robbinsville NJ, US
Assignee:
Purdue Pharma L.P. - Stamford CT
International Classification:
A61K 31/535
US Classification:
5142345
Abstract:
The invention relates to compounds of formulae I(a)-I(d):.
Laykea Tafesse from Trenton, NJ, age ~53 Get Report