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Michael P Kirkup

from Yardley, PA
Age ~74

Michael Kirkup Phones & Addresses

  • 1006 Randolph Dr, Morrisville, PA 19067 (215) 493-2352
  • Yardley, PA
  • 101 Engleside Ave, Beach Haven, NJ 08008 (609) 492-5384
  • 32 Sapphire Dr, West Windsor, NJ 08550 (609) 799-5536 (609) 799-8974
  • Princeton Junction, NJ
  • Bridgewater, NJ
  • Bristol, PA
  • Buck, PA
  • Ocean, NJ
  • Somerset, NJ

Work

Position: Professional/Technical

Education

Degree: Graduate or professional degree

Industries

Pharmaceuticals

Resumes

Resumes

Michael Kirkup Photo 1

Pharmaceuticals Professional

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Location:
Greater Philadelphia Area
Industry:
Pharmaceuticals

Business Records

Name / Title
Company / Classification
Phones & Addresses
Michael Kirkup
Mbr
The Chemistry Research Solution LLC
Research · Contract Research Organization (Cro) Medicinal Chemistry Process Chemistry Custom Synthesis Preclnical and Clinical Compound
360 George Patterson Blvd SUITE 101-E, Bristol, PA 19007
360 George Patterson Dr, Edgely, PA 19007
(215) 788-3603

Publications

Us Patents

Stereospecific Preparation Of (3S,4R,5R)-3-(1-Hydroxyethyl)-4-Benzoyloxy-Azeridinones From L-(-)-Theonine

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US Patent:
48824291, Nov 21, 1989
Filed:
Mar 3, 1986
Appl. No.:
6/835392
Inventors:
Stuart W. McCombie - Caldwell NJ
Michael P. Kirkup - Somerset NJ
Amy Sommese Boland - Pittsburgh PA
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
C07D20508
C07B 4112
C07B 3710
A61K30124
US Classification:
540357
Abstract:
Azetidinones represented by the formula ##STR1## are prepared by a multistep process from L-(-)-theonine via an epoxyamide.

6-(Hydroxyethyl)-2-(Heterocyclylthio)-Penem-3-Carboxylates

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US Patent:
48066370, Feb 21, 1989
Filed:
Mar 17, 1986
Appl. No.:
6/840305
Inventors:
Michael P. Kirkup - Somerset NJ
Amy S. Boland - Pittsburgh PA
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
C07D49900
A61K 31425
US Classification:
540310
Abstract:
There is disclosed antibacterial compounds represented by the formula ##STR1## and pharmaceutically acceptable salts or pharmaceutically acceptable esters thereof, wherein: X represents oxygen, sulfur, ##STR2## wherein R is hydrogen, loweralkyl, acetate or methoxycarbonyl; Y is cis, trans or mixtures thereof and is selected from hydroxy, lower alkoxy, aminocarbamoyloxy, methoxycarbonylamino, lower alkylcarbonyloxy, lower alkylcarbonylamino and loweralkylsulfonylamino; and the wavy lines indicate cis, trans or mixtures thereof.

Intermediate Compounds For Preparing Penems And Carbapenems

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US Patent:
48763659, Oct 24, 1989
Filed:
Dec 5, 1988
Appl. No.:
7/279751
Inventors:
Michael P. Kirkup - Somerset NJ
Stuart W. McCombie - Caldwell NJ
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
C07D30302
US Classification:
549215
Abstract:
Novel and useful silylenol intermediates for preparing penem and carbapenem antibacterials and a process for making selected intermediates are disclosed.

Substituted Azetidinone Compounds Useful As Hypocholesterolemic Agents

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US Patent:
56271760, May 6, 1997
Filed:
Mar 13, 1995
Appl. No.:
8/403081
Inventors:
Michael P. Kirkup - West Windsor NJ
Sundeep Dugar - Bridgewater NJ
Assignee:
Schering Corporation - Kenilworth NJ
International Classification:
A61K 31395
C07D20508
C07D40306
C07D40304
US Classification:
514210
Abstract:
Substituted azetidinone hypocholesterolemic agents of the formula ##STR1## or a pharmaceutically acceptable salt thereof, wherein: Ar. sup. 1 is R. sup. 3 -substituted aryl; Ar. sup. 2 is R. sup. 4 -substituted aryl; Ar. sup. 3 is R. sup. 5 -substituted aryl; Y and Z are independently --CH. sub. 2 --, --CH(lower alkyl)-- or --C(dilower alkyl)--; A is --O--, --S--, --S(O)-- or --S(O). sub. 2 --; R. sup. 1 is --OR. sup. 6, --O(CO)R. sup. 6, --O(CO)OR. sup. 9 or --O(CO)NR. sup. 6 R. sup. 7 ; R. sup. 2 is hydrogen, lower alkyl or aryl; or R. sup. 1 and R. sub. 2 together are. dbd. O; q is 1, 2 or 3; p is 0, 1,2, 3 or 4; R. sup. 5 is 1-3 substitutes independently selected from --OR. sup. 6, --O(CO)R. sup. 6, --O(CO)OR. sup. 9, --O(CH. sub. 2). sub. 1-5 OR. sup.

Improved Process For The Preparation Of Treprostinil And Derivatives Thereof

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US Patent:
20150126761, May 7, 2015
Filed:
May 22, 2013
Appl. No.:
14/401826
Inventors:
- Luxembourg, LU
Michael Kirkup - Bristol PA, US
Michael Marella - Bristol PA, US
Sanjeevani Ghone - Bristol PA, US
International Classification:
C07C 51/377
C07C 59/72
C07F 7/18
US Classification:
556436, 562499, 556482, 556466
Abstract:
A method for the preparation of treprostinil and its derivatives is described. In contrast to prior art, this method utilizes an easily scalable enzymatic resolution of a key intermediate for making these compounds. Another significant improvement of the described method over prior methods is the regioselective Claisen rearrangement of a 5-allyloxy-benzaldehyde precursor, which is facilitated by a bromo substituent in 2-position.
Michael P Kirkup from Yardley, PA, age ~74 Get Report