Inventors:
Ingrid Price Buchler - Cambridge MA, US
Michael Joseph Hayes - Saint Charles MO, US
Shridhar Gajanan Hegde - Germantown TN, US
Susan Landis Hockerman - Kirkwood MO, US
Darin Eugene Jones - Baldwin MO, US
Steven Wade Kortum - Groton CT, US
Joseph Gerace Rico - Kalamazoo MI, US
Ruth Elizabeth TenBrink - Labadie MO, US
Kun Ken Wu - Chesterfield MO, US
International Classification:
A61K 31/541
C07D 231/56
C07D 413/06
C07D 401/06
C07D 401/10
C07D 413/12
C07D 471/04
C07D 413/10
C07D 405/12
C07D 403/12
C07D 401/12
C07D 417/12
A61P 29/00
A61K 31/416
A61K 31/422
A61K 31/4439
A61K 31/4245
A61K 31/437
A61K 31/41
A61K 31/5377
A61K 31/454
A61K 31/496
A61K 31/4178
A61K 31/513
A61K 31/4196
A61K 31/4192
A61K 31/427
A61K 31/433
US Classification:
51421018, 5483625, 548247, 5462757, 548143, 546120, 548236, 548253, 548131, 544140, 544371, 544 582, 5483117, 548229, 544319, 5482664, 5482624, 548255, 548214, 548139, 514406, 514378, 514338, 514364, 514303, 514374, 514381, 5142345, 514322, 51425406, 5142282, 514402, 514376, 514269, 514383, 514372, 514363
Abstract:
This invention relates to compounds, pharmaceutical compositions and methods for the treatment of a condition mediated by CB1 receptor activity in a mammalian subject including a human, which comprises administering to a mammal in need of such treatment a therapeutically effective amount of the compound of formula (I) wherein R, Rand Rare as defined in this specification.
