US Patent:
20120020889, Jan 26, 2012
Inventors:
Jennifer R. Cochran - Stanford CA, US
Adam Silverman - Redwood City CA, US
Douglas Jones - Cambridge MA, US
Niv Papo - Palo Alto CA, US
International Classification:
A61K 49/00
A61K 38/18
C12N 15/62
C12N 5/071
A61P 17/06
C40B 30/04
A61P 35/00
A61P 27/02
A61P 19/02
C07K 19/00
G01N 33/574
US Classification:
424 91, 530399, 514 81, 536 234, 435375, 435 723, 506 9
Abstract:
Polypeptides comprising variant vascular endothelial growth factor sequences are provided. The polypeptides are useful in cancer imaging, cancer diagnosis, monitoring and treatment as well as treatment of diseases characterized by excessive neovascularization.