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Paul F Widboom

from Hanover, NH
Age ~43

Paul Widboom Phones & Addresses

  • 3 Ledge Rd, Hanover, NH 03755
  • Lebanon, NH
  • 2 M Street Pl, Boston, MA 02127 (617) 268-4195
  • 298 K St, Boston, MA 02127 (617) 269-1093
  • South Boston, MA
  • Rochester, NY
  • Penn Yan, NY
  • 232 David Ave, Rochester, NY 14620 (585) 259-5748

Work

Company: Adimab, llc Aug 2013 Position: Scientist ii

Education

Degree: PhD School / High School: Boston College 2003 to 2008 Specialities: Chemistry

Skills

Protein Engineering • Protein Chemistry • Structural Biology • Chemical Biology • Protein Purification

Industries

Biotechnology

Resumes

Resumes

Paul Widboom Photo 1

Associate Director

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Location:
7 Lucent Dr, Lebanon, NH 03756
Industry:
Biotechnology
Work:
Adimab, LLC since Aug 2013
Scientist II

Adimab, LLC since Nov 2010
Scientist I

Massachusetts Institute of Technology Jan 2009 - Feb 2011
Post-Doctoral Associate
Education:
Boston College 2003 - 2008
PhD, Chemistry
Wheaton College 1999 - 2003
BS, Chemistry
High School
Skills:
Protein Engineering
Protein Chemistry
Structural Biology
Chemical Biology
Protein Purification

Publications

Us Patents

Anti-Cd39 Antibodies, Compositions Comprising Anti-Cd39 Antibodies And Methods Of Using Anti-Cd39 Antibodies

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US Patent:
20220340680, Oct 27, 2022
Filed:
Apr 20, 2022
Appl. No.:
17/725142
Inventors:
- South San Francisco CA, US
Maria Kovalenko - South San Francisco CA, US
John Corbin - South San Francisco CA, US
Courtney Beers - South San Francisco CA, US
Paul Fredrick Widboom - Hanover NH, US
Joseph Robert Warfield - White River Junction VT, US
International Classification:
C07K 16/28
G01N 33/566
A61K 39/395
A61P 37/04
C12N 15/11
C12N 15/63
Abstract:
Provided herein are antibodies with binding specificity for CD39 and compositions comprising the antibodies, including pharmaceutical compositions, diagnostic compositions and kits. Also provided are methods of using anti-CD39 antibodies for therapeutic and diagnostic purposes.

Anti-Cd45 Antibodies And Conjugates Thereof

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US Patent:
20220267441, Aug 25, 2022
Filed:
Oct 22, 2021
Appl. No.:
17/452028
Inventors:
- Cambridge MA, US
Michael Cooke - Boston MA, US
Charlotte Fenton McDonagh - Winchester MA, US
Rahul Palchaudhuri - Somerville MA, US
Rajiv Panwar - Acton MA, US
Bradley Pearse - Somerville MA, US
Paul Fredrick Widboom - Hanover NH, US
Patricia Ann Cruite - Medford MA, US
International Classification:
C07K 16/28
A61K 47/68
A61K 35/28
A61P 35/02
A61P 37/06
Abstract:
Disclosed are anti-CD45 antibodies, antigen binding fragments thereof, and antibody drug conjugates (ADCs) that specifically bind to human CD45. Such antibodies and ADCs are useful in therapeutic methods, including methods of depleting CD45+ cells from a patient. The compositions and methods described herein can be used to treat a disorder directly, for instance, by depleting a population of CD45+ cancer cells or autoimmune cells. The compositions and methods described herein can also be used to prepare a patient for hematopoietic stem cell transplant therapy, and to improve the engraftment of hematopoietic stem cell transplants, by selectively depleting endogenous CD45+ cells prior to the transplant procedure.

Anti-Cd39 Antibodies, Compositions Comprising Anti-Cd39 Antibodies And Methods Of Using Anti-Cd39 Antibodies

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US Patent:
20210403593, Dec 30, 2021
Filed:
Sep 7, 2021
Appl. No.:
17/468366
Inventors:
- South San Francisco CA, US
Maria Kovalenko - South San Francisco CA, US
John Corbin - South San Francisco CA, US
Courtney Beers - South San Francisco CA, US
Paul Fredrick Widboom - Lebanon NH, US
Joseph Robert Warfield - Lebanon NH, US
International Classification:
C07K 16/28
G01N 33/566
A61K 39/395
A61P 37/04
C12N 15/11
C12N 15/63
Abstract:
Provided herein are antibodies that selectively bind to CD39 and its isoforms and homologs, and compositions comprising the antibodies. Also provided are methods of using the antibodies, such as therapeutic and diagnostic methods.

Anti-Hla-G Antibodies, Compositions Comprising Anti-Hla-G Antibodies And Methods Of Using Anti-Hla-G Antibodies

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US Patent:
20210340259, Nov 4, 2021
Filed:
Sep 26, 2019
Appl. No.:
17/280755
Inventors:
- South San Francisco CA, US
John Corbin - South San Francisco CA, US
Doug Hodges - South San Francisco CA, US
Achim Moesta - South San Francisco CA, US
Vanessa Soros - South San Francisco CA, US
Paul Fredrick Widboom - Lebanon NH, US
Joseph Robert Warfield - Lebanon NH, US
International Classification:
C07K 16/28
A61K 45/06
A61P 35/00
Abstract:
Provided herein are antibodies that selectively bind to HLA-G and and compositions comprising the antibodies. Also provided are methods of using the antibodies, such as therapeutic and diagnostic methods.

Antibodies That Bind Cd277 And Uses Thereof

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US Patent:
20210309746, Oct 7, 2021
Filed:
Aug 9, 2019
Appl. No.:
17/267066
Inventors:
- Brighton MA, US
Paul Widboom - Lebanon NH, US
Michael March Schmidt - Wellesley MA, US
International Classification:
C07K 16/28
Abstract:
The present disclosure relates to, inter alia, compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to CD277, for treating, or ameliorating one or more symptoms of cancer.

Anti-Cd39 Antibodies, Compositions Comprising Anti-Cd39 Antbodies And Methods Of Using Anti-Cd39 Antibodies

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US Patent:
20210009708, Jan 14, 2021
Filed:
Jul 30, 2018
Appl. No.:
16/635526
Inventors:
- South San Francisco CA, US
Maria KOVALENKO - Portola Valley CA, US
John CORBIN - Oakland CA, US
Courtney BEERS - San Francisco CA, US
Paul Fredrick WIDBOOM - Hanover NH, US
Joseph Robert WARFIELD - White River Junction VT, US
International Classification:
C07K 16/28
A61K 39/395
A61K 45/06
Abstract:
Provided herein are antibodies that selectively bind to CD39 and its isoforms and homologs, and compositions comprising the antibodies. Also provided are methods of using the antibodies, such as therapeutic and diagnostic methods.

Agonist Antibodies That Bind Human Cd137 And Uses Thereof

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US Patent:
20200306374, Oct 1, 2020
Filed:
Jun 8, 2020
Appl. No.:
16/895239
Inventors:
- Cambridge MA, US
Paul Widboom - Lebanon NH, US
Michael March Schmidt - Wellesley MA, US
Jason M. Lajoie - Brighton MA, US
Cheuk Lun Leung - Quincy MA, US
Ugur Eskiocak - Somerville MA, US
International Classification:
A61K 39/395
C07K 16/28
A61P 35/00
A61K 39/00
A61K 35/17
C12N 15/79
Abstract:
The present disclosure relates to, inter alia, compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to an epitope of CD137 and agonize CD137, and to use of the compounds in methods for treating, or ameliorating one or more symptoms of, cancer.

Agonist Antibodies That Bind Human Cd137 And Uses Thereof

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US Patent:
20200046833, Feb 13, 2020
Filed:
Oct 30, 2019
Appl. No.:
16/669061
Inventors:
- Cambridge MA, US
Paul WIDBOOM - Lebanon NH, US
Michael March SCHMIDT - Cambridge MA, US
Jason M. LAJOIE - Cambridge MA, US
Cheuk Lun LEUNG - Cambridge MA, US
Ugur ESKIOCAK - Cambridge MA, US
International Classification:
A61K 39/395
C12N 15/79
C07K 16/28
A61K 35/17
A61K 39/00
A61P 35/00
Abstract:
The present disclosure relates to, inter alia, compounds (e.g., antibodies, or antigen-binding fragments thereof) that bind to an epitope of CD137 and agonize CD137, and to use of the compounds in methods for treating, or ameliorating one or more symptoms of, cancer.
Paul F Widboom from Hanover, NH, age ~43 Get Report