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Punit P Seth

from Boston, MA
Age ~52
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Also known as:
Punit D Seth, Punit P Totlani, Seth P Punit
Connected to:
Bekoe Seth, 87Bernice O Seth, 103Hemant K Seth, 38Johnny B Seth, 52Ketki Seth, 45Krisha Seth, 37Maria M Seth, 70Mary T Seth, 71Mukul Seth, 46Niti Seth, 77

Punit Seth Phones & Addresses

  • Boston, MA
  • 1600 Sapphire Dr, Carlsbad, CA 92011 (760) 438-7844
  • 6773 Mallee St, Carlsbad, CA 92011
  • 896 Kestral Dr, San Marcos, CA 92078 (760) 744-7563
  • Columbus, OH
  • Iowa City, IA
  • San Diego, CA
  • Sanger, CA
  • 1600 Sapphire Dr, Carlsbad, CA 92011 (760) 744-7563

Work

Position: Executive, Administrative, and Managerial Occupations

Education

Degree: Associate degree or higher

Resumes

Resumes

Punit Seth Photo 1

Vice President, Medicinal Chemistry

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Location:
Carlsbad, CA
Industry:
Biotechnology
Work:
Isis Pharmaceuticals
Vice President, Medicinal Chemistry
Ionis Pharmaceuticals, Inc. Jan 2013 - Mar 2016
Executive Director, Medicinal Chemistry
Education:
The Ohio State University 1993 - 1999
Doctorates, Doctor of Philosophy, Organic Chemistry
Skills:
Drug Discovery
Biotechnology
Medicinal Chemistry
Organic Synthesis
Drug Design
Life Sciences
Lc Ms
Pharmaceutical Industry
Drug Development
Organic Chemistry
Lifesciences
Hplc
Biochemistry
Nmr
Languages:
Hindi
Punit Seth Photo 2

Punit Seth

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Publications

Us Patents

6-Modified Bicyclic Nucleic Acid Analogs

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US Patent:
7399845, Jul 15, 2008
Filed:
Jan 27, 2007
Appl. No.:
11/627964
Inventors:
Punit P. Seth - San Marcos CA, US
Eric E. Swayze - Carlsbad CA, US
Assignee:
Isis Pharmaceuticals, Inc. - Carlsbad CA
International Classification:
C07H 19/00
C07H 21/00
A01N 43/04
A61K 31/70
US Classification:
536 221, 536 231, 514 43
Abstract:
The present invention provides 6-modified bicyclic nucleoside analogs and oligomeric compounds comprising these nucleoside analogs. In preferred embodiments the nucleoside analogs have either (R) or (S)-chirality at the 6-position. These bicyclicnucleoside analogs are useful for enhancing properties of oligomeric compounds including nuclease resistance.

Antimicrobial Biaryl Compounds

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US Patent:
7432264, Oct 7, 2008
Filed:
Aug 9, 2004
Appl. No.:
10/914256
Inventors:
Elizabeth Anne Jefferson - La Jolla CA, US
Eric E. Swayze - Carlsbad CA, US
Punit P. Seth - San Marcos CA, US
Assignee:
Isis Pharmaceuticals, Inc. - Carlsbad CA
International Classification:
A61P 31/04
A61K 31/495
A61K 31/497
A61K 31/50
C07D 241/02
C07D 241/36
C07D 401/00
C07D 405/00
C07D 409/00
C07D 411/00
C07D 413/00
C07D 417/00
C07D 419/00
US Classification:
514249, 51425211, 51425213, 51425306, 51425311, 51425401, 51425403, 544353, 544354, 544357, 544363, 544364, 544367, 544379
Abstract:
Provided are antibacterial biaryl compounds having micromolar MIC activity against Gram-negative and Gram-positive pathogens, including a methicillin-resistant strain.

5′-Modified Bicyclic Nucleic Acid Analogs

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US Patent:
7547684, Jun 16, 2009
Filed:
May 10, 2007
Appl. No.:
11/747057
Inventors:
Punit P. Seth - San Marcos CA, US
Eric E. Swayze - Carlsbad CA, US
Balkrishen Bhat - Carlsbad CA, US
Assignee:
Isis Pharmaceuticals, Inc. - Carlsbad CA
International Classification:
A01N 43/04
A61K 31/70
US Classification:
514 44, 514 42, 514 43, 536 221
Abstract:
The present invention provides 5′-modified bicyclic nucleoside analogs and oligomeric compounds comprising at least one of these nucleoside analogs. In preferred embodiments the nucleoside analogs have either (R) or (S)-chirality at the 5′-carbon. These bicyclic nucleoside analogs are useful for enhancing properties of oligomeric compounds including for example enhanced nuclease resistance.

Compounds And Methods For Synthesis Of Bicyclic Nucleic Acid Analogs

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US Patent:
7569686, Aug 4, 2009
Filed:
May 10, 2007
Appl. No.:
11/747042
Inventors:
Balkrishen Bhat - Carlsbad CA, US
Jie Xia - Carlsbad CA, US
Punit P. Seth - San Marcos CA, US
Guillermo Vasquez - Oceanside CA, US
Michael T. Migawa - Carlsbad CA, US
Charles Allerson - San Diego CA, US
Thazha P. Prakash - Carlsbad CA, US
Eric E. Swayze - Carlsbad CA, US
Assignee:
Isis Pharmaceuticals, Inc. - Carlsbad CA
International Classification:
C07H 21/00
US Classification:
536 253, 536 181, 536 185, 536 186, 536 221
Abstract:
The present invention provides compounds and methods of using them for preparing bicyclic nucleosides. The bicyclic nucleosides are useful for preparing chemically modified oligomeric compounds. Oligomeric compounds comprising these bicyclic nucleosides have enhanced properties such as increased nuclease resistance.

Benzimidazoles And Analogs Thereof As Antivirals

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US Patent:
7642265, Jan 5, 2010
Filed:
Sep 22, 2004
Appl. No.:
10/946757
Inventors:
Punit P. Seth - San Marcos CA, US
Elizabeth Anne Jefferson - La Jolla CA, US
Richard H. Griffey - Vista CA, US
Eric E. Swayze - Carlsbad CA, US
Assignee:
Isis Pharmaceuticals, Inc. - Carlsbad CA
International Classification:
A61P 31/12
A61K 31/4188
C07D 491/12
US Classification:
514257, 544247
Abstract:
Provided are compounds of the formula:.

Bis-Modified Bicyclic Nucleic Acid Analogs

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US Patent:
7666854, Feb 23, 2010
Filed:
Dec 9, 2008
Appl. No.:
12/331226
Inventors:
Punit P. Seth - Carlsbad CA, US
Eric E. Swayze - Carlsbad CA, US
Assignee:
Isis Pharmaceuticals, Inc. - Carlsbad CA
International Classification:
A01N 43/04
A61K 31/70
US Classification:
514 44, 514 42, 514 43, 536 221
Abstract:
The present disclosure describes bis-modified bicyclic nucleosides and oligomeric compounds that can be prepared comprising at least one of these bis-modified bicyclic nucleosides. More particularly, the bis-modified bicyclic nucleosides have at least one substituent group at the 5′-methylene and on the bridge methylene and can be chiral. These bis-modified bicyclic nucleosides are expected to be useful for enhancing one or more property of oligomeric compounds including for example enhancing nuclease resistance.

6-Modified Bicyclic Nucleic Acid Analogs

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US Patent:
7741457, Jun 22, 2010
Filed:
May 29, 2008
Appl. No.:
12/129154
Inventors:
Punit P. Seth - San Marcos CA, US
Eric E. Swayze - Carlsbad CA, US
Assignee:
Isis Pharmaceuticals, Inc. - Carlsbad CA
International Classification:
C07H 19/00
C07H 21/00
US Classification:
536 221, 536 231, 514 43
Abstract:
The present invention provides 6-modified bicyclic nucleoside analogs and oligomeric compounds comprising these nucleoside analogs. In preferred embodiments the nucleoside analogs have either (R) or (S)-chirality at the 6-position. These bicyclicnucleoside analogs are useful for enhancing properties of oligomeric compounds including nuclease resistance.

5′-Modified Bicyclic Nucleic Acid Analogs

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US Patent:
7750131, Jul 6, 2010
Filed:
Mar 19, 2009
Appl. No.:
12/407643
Inventors:
Punit P. Seth - Carlsbad CA, US
Eric E. Swayze - Encinitas CA, US
Balkrishen Bhat - Carlsbad CA, US
Assignee:
Isis Pharmaceuticals, Inc. - Carlsbad CA
International Classification:
C07H 19/00
C07H 21/00
US Classification:
536 221, 514 42, 514 43, 514 44
Abstract:
The present invention provides 5′-modified bicyclic nucleoside analogs and oligomeric compounds comprising at least one of these nucleoside analogs. In preferred embodiments the nucleoside analogs have either (R) or (S)-chirality at the 5′-carbon. These bicyclic nucleoside analogs are useful for enhancing properties of oligomeric compounds including for example enhanced nuclease resistance.
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Punit P Seth from Boston, MA, age ~52 Get Report