James Wynne

6686494, Feb 3, 2004

Mar 6, 2003

10/384928

James W. Wynne - Alexandria VA
Arthur W. Snow - Alexandria VA

The United States of America as represented by the Secretary of the Navy - Washington DC

C07C31500

558232, 562555, 562556, 562 27, 560 12, 560132

A method for preparing S-alkyl and S-aryl thiocarbamates comprising reacting a precursor thiol reagent with trichloroacetyl chloride to produce an S-alkyl and S-aryl trichloroacetyl thioester intermediate, which is reacted with an amine to yield the corresponding thiocarbamate product. Also disclosed is the method for preparing S-alkyl and S-aryl thiocarbamates comprising reacting an amine with trichloroacetyl chloride to produce a trichloroacetamide intermediate, which is then reacted with the precursor thiol to yield the corresponding thiocarbamate product.

6872830, Mar 29, 2005

May 29, 2003

10/446715

James H. Wynne - Alexandria VA, US
Wayne M. Stalick - Fairfax VA, US

George Mason University - Fairfax VA

C07D487/04

546 81, 514292

The present invention concerns the compounds of the formula: and the prodrug and salts thereof, wherein R may be a hydroxyl or other pendent group and Ar is an aryl. The compositions may be adapted for the treatment of neurodegenerative diseases. Further, the compositions may be adapted as a pharmaceutical such as an antipsychotic pharmaceutical, an antibiotic pharmaceutical, an antiviral pharmaceutical or an antitumor pharmaceutical.

7060830, Jun 13, 2006

Feb 9, 2005

11/053426

James H. Wynne - Alexandria VA, US
Wayne M. Stalick - Fairfax VA, US

George Mason Intellectual Properties, Inc. - Fairfax VA

C07D 471/04
C07D 487/04

546 81, 546 79, 546 80

The present invention concerns the compounds of the formula:.

7189867, Mar 13, 2007

Sep 19, 2006

11/532950

James H Wynne - Alexandria VA, US
Arthur W Snow - Alexandria VA, US

The United States of America as represented by the Secretary of the Navy - Washington DC

C07C 321/00
C07F 7/04

556429, 556113, 568 21, 568 62

A compound having the formula CF—CH(OH)—CH—(L)—CH—SH or a disulfide thereof. Each L is substituted or unsubstituted methylene, substituted or unsubstituted oxyalkylene, and alkyl-substituted or unsubstituted siloxanylene. The compound is free of carboxysilane linkages. The value of n is a positive integer. A metal surface having the group CF—CH(OH)—CH—(L)—CH—S— bound thereto. A method of making CF—CH(OH)—CH—(L)—CH—SH by: reacting OHC—CH—(L)—CH—X with (trifluoromethyl)trialkylsilane to form CF—CH(OH)—CH—(L)—CH—X; reacting the intermediate with a thiocarbonyl compound to form an adduct; and hydrolyzing the adduct followed by protonation. X is a halogen.

7339015, Mar 4, 2008

Jul 14, 2005

11/183305

James H. Wynne - Alexandria VA, US
Arthur W. Snow - Alexandria VA, US
Leonard J. Buckley - Fairfax Station VA, US

The United States of America as represented by the Secretary of the Navy - Washington DC

C08F 126/00

526312, 526329, 5263296, 526332

A coating having an adhesive hydrophilic polymer and an amphiphilic additive. The amphiphilic additive has a hydrophilic chain, a biocidal functional group bonded to the hydrophilic chain, and a hydrophobic moiety bonded to the hydrophilic chain or to the biocidal functional group. A method of forming a biocidal surface by providing an article, and coating the article with the above coating. A compound having the formula:Y—(O—CH—CH)—R—(CH)—CH. Y is CHor H. R is.

7452951, Nov 18, 2008

Jan 8, 2008

11/970543

James H Wynne - Alexandria VA, US
Arthur W Snow - Alexandria VA, US
Leonard J Buckley - Fairfax Station VA, US

The United States of America as represented by the Secretary of the Navy - Washington DC

C08F 126/00

526312, 526329, 5263296, 526332

A coating having an adhesive hydrophilic polymer and an amphiphilic additive. The amphiphilic additive has a hydrophilic chain, a biocidal functional group bonded to the hydrophilic chain, and a hydrophobic moiety bonded to the hydrophilic chain or to the biocidal functional group. A method of forming a biocidal surface by providing an article, and coating the article with the above coating. A compound having the formula:Y—(O—CH—CH)—R—(CH)—CH. Y is CHor H. R is.

7682519, Mar 23, 2010

Feb 28, 2006

11/307919

James Wynne - Alexandria VA, US
Barry Spargo - Washington DC, US
Christopher Lloyd - Springfield VA, US
Marc Laplante - Washington DC, US

The United States of America as represented by the Secretary of the Navy - Washington DC

C09K 3/22
G03C 11/08
C09K 21/00

252 881, 252 882, 252381, 252606

A composition of matter containing a solution made from: from about 18 to about 70 wt % of a sugar; from about 2 to about 10 wt % of a water-soluble polysaccharide; from about 0. 1 to about 1 wt % of a phosphate; from about 0. 01 to about 1 wt % of a surfactant; and from about 18 wt % to remainder of water. A method for dust and sand abatement and erosion prevention by: providing the above solution, applying the solution to sand or dust particles wherein the solution binds to the particles; and allowing the solution to bind to the sand or dust particles and to dry thereby forming a hardened crust.

7741503, Jun 22, 2010

May 16, 2007

11/749252

James H Wynne - Alexandria VA, US
Christopher T Lloyd - Springfield VA, US
Joseph P. Buckley - Fairfax Station VA, US
Ramesh R. Pant - Fairfax VA, US
Brian T. Rasley - Fairbanks AK, US

The United States of America as represented by the Secretary of the Navy - Washington DC

C07F 7/10

556425, 556413, 556400

A compound having the formula:.