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Richard Jay Smeyne

from Elkins Park, PA
Age ~65

Richard Smeyne Phones & Addresses

  • 534 Elkins Ave, Elkins Park, PA 19027 (901) 351-4152
  • Memphis, TN
  • 10394 Hulsey Cir, Collierville, TN 38017 (901) 853-4152
  • Denville, NJ
  • Coaldale, PA
  • Philadelphia, PA
  • Newtown, PA
  • 10394 Hulsey Cir, Collierville, TN 38017

Resumes

Resumes

Richard Smeyne Photo 1

Professor

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Location:
10394 Hulsey Cir, Collierville, TN 38017
Industry:
Research
Work:
Thomas Jefferson University
Professor

Saint Jude Children's Hospital Jul 1996 - Jul 2016
Member

Roche 1994 - 1996
Head Neurogenetics

Bristol-Myers Squibb 1992 - 1994
Lab Head
Education:
Thomas Jefferson University Hospitals 1984 - 1989
Doctorates, Doctor of Philosophy, Anatomy
University of Hartford 1981 - 1983
Masters, Psychology
Saint Joseph's University 1977 - 1981
Bachelors, Bachelor of Science, Biology
Skills:
Cell Biology
Neuroscience
Molecular Biology
Immunohistochemistry
Life Sciences
Pharmacology
Lifesciences
Biochemistry
Cell Culture
Genetics
Cancer
Translational Research
Cell
Microscopy
In Vivo
Western Blotting
Drug Discovery
Science
Research
Flow Cytometry
Pcr
Protein Chemistry
Biotechnology
Immunology
Elisa
Tissue Culture
Richard Smeyne Photo 2

Associate Member

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Location:
Collierville, TN
Industry:
Research
Work:
SJCRH
Associate Member

Hoffmann-La Roche 1995 - 1996
Head, Neurogenetics
Education:
Jefferson Medical College of Thomas Jefferson University 1984 - 1989
University of Hartford

Business Records

Name / Title
Company / Classification
Phones & Addresses
Richard Smeyne
Owner
Richard J Smeyne
Scientific
10394 Hulsey Cir, Piperton, TN 38017

Publications

Us Patents

Cells That Lack P19Ink4D And P27Kip1 Activity And Methods Of Use Thereof

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US Patent:
6589505, Jul 8, 2003
Filed:
Jan 14, 2000
Appl. No.:
09/483597
Inventors:
Martine F. Roussel - Memphis TN
Richard Smeyne - Collierville TN
Frederique Zindy - Memphis TN
Justine Cunningham - Memphis TN
Neil Segil - Altadena CA
Ping Chen - Arcadia CA
Assignee:
St. Jude Childrens Research Hospital - Memphis TN
International Classification:
A61K 4900
US Classification:
424 92, 424 91, 435325, 4353201, 435375, 800 3, 800 8, 800 9, 800 14
Abstract:
Non-human animals that have been manipulated so as not to express a functional p19 and p27 proteins are described. One particular non-human animal exemplified is a p19 -double null, p27 -double null mouse. Such knockout mice exhibit bradykinesia, proprioceptive abnormalities, seizure-like activity, and generally die 14-24 days after birth. In addition, mammalian cells having the p19 -double null, p27 -double null genotype are characterized. Methods of making and using the non-human knockout animals and cells are disclosed.

Method For Determining Sensitivity To Environmental Toxins And Susceptibility To Parkinson's Disease

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US Patent:
20040219600, Nov 4, 2004
Filed:
Dec 12, 2003
Appl. No.:
10/734372
Inventors:
Robert Williams - Memphis TN, US
Richard Smeyne - Collierville TN, US
Michelle Smeyne - Collierville TN, US
Ruby Tharpe - Olive Branch MS, US
Elizabeth Cook - Olive Branch MS, US
International Classification:
G01N033/53
G01N033/567
C12Q001/48
US Classification:
435/007100, 435/015000
Abstract:
The present invention relates to the identification of a gene encoding the protein glutathione S-transferase pi2 as being correlated with the susceptibility to neurotoxicity and concomitantly the risk to develop Parkinson's disease. Based on this correlation, various methods are disclosed, including determining the amount of the one or more glutathione S-transferase present in a biological sample in response to an environmental toxin, to assess the risk to develop Parkinson's disease.

Knockout Mice And Cells That Lack P19Ink4D And P27Kip1 Activity And Methods Of Use Thereof

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US Patent:
62459651, Jun 12, 2001
Filed:
Jan 29, 1999
Appl. No.:
9/240906
Inventors:
Martine F. Roussel - Memphis TN
Richard Smeyne - Collierville TN
Frederique Zindy - Memphis TN
Justine Cunningham - Memphis TN
Assignee:
St. Jude Children's Research Hospital - Memphis TN
International Classification:
G01N 3300
A01K 6700
C12N 1585
C12N 1586
US Classification:
800 18
Abstract:
Non-human animals that have been manipulated so as not to express a functional p19. sup. INK4d and p27. sup. KIP1 proteins are described. One particulat non-human animal exemplified is a p19. sup. INK4d -double null, p27. sup. KIP1 -double null mouse. Such knockout mice exhibit bradykinesia, proprioceptive abnormalties, seizure-like activity, and generally die 14-24 days after birth. In addition, mammalian cells having the p19. sup. INK4d -double null, p27. sup. KIP1 -double null genotype are characterized. Methods of making and using the non-human knockout animals and cells are disclosed.

Method For Detection Of Adenosine And Metabolites Thereof

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US Patent:
20160003797, Jan 7, 2016
Filed:
Feb 28, 2014
Appl. No.:
14/765649
Inventors:
- Memphis TN, US
Richard Jay Smeyne - Collierville TN, US
Assignee:
St. Jude Children's Research Hospital - Memphis TN
International Classification:
G01N 33/487
G01N 27/42
Abstract:
This invention relates is a label-free, enzyme-free, aptamer-free method for simultaneously measuring adenosine, and its intracellular metabolites, e.g., AMP, ADP and ATP, using high pressure liquid chromatography coupled to electrochemical detector (HPLC-ECD).
Richard Jay Smeyne from Elkins Park, PA, age ~65 Get Report