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Sailaja Sreedevi Vanama

from Monroe, NJ
Age ~56

Sailaja Vanama Phones & Addresses

  • 63 Spruce Meadows Dr, Monroe Township, NJ 08831 (732) 605-9197
  • Monroe, NJ
  • Burlington, NJ
  • Mount Laurel, NJ
  • Chelmsford, MA
  • North Chelmsford, MA

Publications

Us Patents

Fusion Proteins Containing Recombinant Cytotoxic Rnases

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US Patent:
8192739, Jun 5, 2012
Filed:
Jun 5, 2009
Appl. No.:
12/479250
Inventors:
David M. Goldenberg - Mendham NJ, US
Hans J. Hansen - Picayune MS, US
Chien-Hsing Ken Chang - Downingtown PA, US
Sailaja S. Vanama - Monroe NJ, US
Edmund A. Rossi - Nutley NJ, US
Assignee:
Immunomedics, Inc. - Morris Plains NJ
International Classification:
C07K 16/46
C07K 16/28
C07K 16/30
C12P 21/08
A61K 39/00
A61K 39/395
C12N 9/22
US Classification:
4241331, 4241341, 4241431, 4241561, 4241921, 4242361, 424199, 424328, 5303873, 53038822, 53038885, 530350
Abstract:
Recombinant immunotoxins containing a cytotoxic RNAse fused to an antibody or antibody fragment may be produced in mammalian cell culture. Surprisingly, immunotoxins containing a cytotoxic RNAse fused to the N-terminus of one antibody variable domain can be prepared and retain the ability to specifically bind antigen. The immunotoxins may be used in a variety of therapeutic methods for treating diseases or syndromes associated with unwanted or inappropriate cell proliferation or activation.

Fusion Proteins Containing Recombinant Cytotoxic Rnases

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US Patent:
20120149085, Jun 14, 2012
Filed:
Feb 22, 2012
Appl. No.:
13/402480
Inventors:
David M. GOLDENBERG - Mendham NJ, US
Hans J. HANSEN - Picayune MS, US
Chien-Hsing Ken CHANG - Downingtown PA, US
Sailaja S. VANAMA - Monroe NJ, US
Edmund A. ROSSI - Nutley NJ, US
Assignee:
IMMUNOMEDICS, INC. - Morris Plains NJ
International Classification:
C12N 9/96
US Classification:
435188
Abstract:
Recombinant immunotoxins containing a cytotoxic RNAse fused to an antibody or antibody fragment may be produced in mammalian cell culture. Surprisingly, immunotoxins containing a cytotoxic RNAse fused to the N-terminus of one antibody variable domain can be prepared and retain the ability to specifically bind antigen. The immunotoxins may be used in a variety of therapeutic methods for treating diseases or syndromes associated with unwanted or inappropriate cell proliferation or activation.

Fusion Proteins Containing Recombinant Cytotoxic Rnases

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US Patent:
20170334996, Nov 23, 2017
Filed:
Aug 2, 2017
Appl. No.:
15/666902
Inventors:
- Morris Plains NJ, US
Hans J. HANSEN - Picayune MS, US
Chien-Hsing Ken CHANG - Downingtown PA, US
Sailaja S. VANAMA - Monroe NJ, US
Edmund A. ROSSI - Nutley NJ, US
International Classification:
C07K 16/28
C12N 9/22
A61K 47/68
Abstract:
Recombinant immunotoxins containing a cytotoxic RNAse fused to an antibody or antibody fragment may be produced in mammalian cell culture. Surprisingly, immunotoxins containing a cytotoxic RNAse fused to the N-terminus of one antibody variable domain can be prepared and retain the ability to specifically bind antigen. The immunotoxins may lie used in a variety of therapeutic methods for treating diseases or syndromes associated with unwanted or inappropriate cell proliferation or activation.
Sailaja Sreedevi Vanama from Monroe, NJ, age ~56 Get Report