US Patent:
20110020362, Jan 27, 2011
Inventors:
Sushil K. Sarna - Houston TX, US
International Classification:
A61K 39/395
A61K 31/36
A61K 31/553
A61K 31/7088
A61K 38/12
A61K 31/417
A61K 31/138
A61K 31/404
A61P 1/00
US Classification:
4241581, 514450, 51421108, 514 44 A, 514 211, 514401, 514652, 514415
Abstract:
The current invention provides mechanisms by which chronic stress induced hypersensitivity exacerbates the symptoms of irritable bowel syndrome. The invention includes methods of treating irritable bowel syndrome using agents which inhibit key molecules involved in the sensitization pathway.