US Patent:
20170367723, Dec 28, 2017
Inventors:
- Baltimore MD, US
Mouen A. Khashab - Towson MD, US
Vivek Kumbhari - Baltimore MD, US
Andreas Oberbach - Leipzig, DE
International Classification:
A61B 17/32
A61B 18/14
A61B 18/00
Abstract:
The present invention is directed to a method of endoscopically ablating/resecting/excluding (A/R/E) the mucosa of the gastric fundus and body. The method of the present invention is intended to cause cellular death to the X/A-like, ghrelin producing and other hormone cells. This is in contrast to present methods to provide only transient ischemia. The use of the method of the present invention results in a more permanent and robust method of reducing ghrelin and other hormone levels. In addition, a method according to the present invention can be used to induce scarring of the gastric fundus which will reduce gastric accommodation of excess food and result in early satiety.