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Vladimir A Koulchin

from Portland, ME
Age ~71

Vladimir Koulchin Phones & Addresses

  • 340 Eastern Promenade, Portland, ME 04101 (207) 773-7492
  • 340 Eastern Promenade APT 224, Portland, ME 04101 (207) 773-7492
  • South Portland, ME
  • Redmond, WA

Resumes

Resumes

Vladimir Koulchin Photo 1

Vp Product Development At Envirologix, Inc.

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Location:
Portland, Maine Area
Industry:
Biotechnology
Experience:
EnviroLogix, Inc. (Privately Held; Biotechnology industry): VP Product Development,  (2008-Present) Chemogen, Inc. (Biotechnology industry): Founder and President, then CSO,  (2000-2007) Immunodiagnostic company developing rapid tests for infectious dise...
Vladimir Koulchin Photo 2

Vladimir Koulchin

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Business Records

Name / Title
Company / Classification
Phones & Addresses
Vladimir Koulchin
VP Product Development
ENVIROLOGIX INC
Mfg Analytical Instruments
500 Riverside Industrial Pkwy, Portland, ME 04103
500 Riverside Indus Pkwy, Portland, ME 04103
(207) 797-0300

Publications

Us Patents

Enriched Antibody For Detecting Mycobacterial Infection, Methods Of Use And Diagnostic Test Employing Same

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US Patent:
7335480, Feb 26, 2008
Filed:
Jul 20, 2005
Appl. No.:
11/186933
Inventors:
Vladimir A. Koulchin - Portland ME, US
Elena V. Molokova - Portland ME, US
Jill L. Kerrick - Scarborough ME, US
Assignee:
Chemogen, Inc. - South Portland ME
International Classification:
G01N 33/53
A61K 39/04
US Classification:
435 71, 435 4, 435 72, 435 732, 435 79, 435 792, 424 91, 424 92, 4241301, 4241641, 4241681, 4241841, 4242341, 4242481
Abstract:
The disclosed technology provides an enriched antibody population, highly specific for an antigen of a surface polysaccharide, from a mycobacterium. In a related embodiment, the antibody is enriched by having been raised in an environment that maintains antigenically active antigen. These antibodies may be used in an immunoreactive environment for detecting the presence of a mycobacterial infection in a sample from a subject.

Enriched Antibody For Detecting Mycobacterial Infection, Methods Of Use And Diagnostic Test Employing Same

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US Patent:
7615222, Nov 10, 2009
Filed:
Oct 31, 2007
Appl. No.:
11/932722
Inventors:
Vladimir A. Koulchin - Portland ME, US
Elena V. Molokova - Portland ME, US
Jill L. Kerrick - Scarborough ME, US
Assignee:
Chemogen, Inc. - South Portland ME
International Classification:
A61K 39/40
A61K 39/04
A61K 39/02
US Classification:
4241681, 424 91, 424 92, 4241301, 4241641, 4241841, 4242341, 4242481, 435 4, 435 71, 435 72, 435 732, 435 79, 435 792
Abstract:
The disclosed technology provides an enriched antibody population, highly specific for an antigen of a surface polysaccharide, from a mycobacterium. In a related embodiment, the antibody is enriched by having been raised in an environment that maintains antigenically active antigen. These antibodies may be used in an immunoreactive environment for detecting the presence of a mycobacterial infection in a sample from a subject.

Method Of Preparing Enriched Antibodies For Detecting Mycobacterial Infection

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US Patent:
8057797, Nov 15, 2011
Filed:
Oct 19, 2009
Appl. No.:
12/581603
Inventors:
Vladimir A. Koulchin - Portland ME, US
Elena V. Molokova - Portland ME, US
Jill L. Kerrick - Scarborough ME, US
Assignee:
Chemogen, Inc. - Waltham MA
International Classification:
A61K 39/40
A61K 39/04
A61K 39/395
US Classification:
4241681, 424 91, 424 92, 4241301, 4241641, 4241841, 4242341, 4242481, 435 4, 435 71, 435 72, 435 732, 435 79, 435 792
Abstract:
The disclosed technology provides an enriched antibody population, highly specific for an antigen of a surface polysaccharide, from a mycobacterium. In a related embodiment, the antibody is enriched by having been raised in an environment that maintains antigenically active antigen. These antibodies may be used in an immunoreactive environment for detecting the presence of a mycobacterial infection in a sample from a subject.

Process And Materials For The Rapid Detection Of Streptococcus Pneumoniae Employing Purified Antigen-Specific Antibodies

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US Patent:
20050148039, Jul 7, 2005
Filed:
Nov 16, 2004
Appl. No.:
10/989050
Inventors:
Norman Moore - North Berwick ME, US
Mary Fent - Cumberland Center ME, US
Vladimir Koulchin - Portland ME, US
Elena Molokova - Portland ME, US
International Classification:
C07K016/12
G01N033/554
G01N033/569
C08B037/00
US Classification:
435007320, 530388400, 536053000
Abstract:
Disclosed is a cell wall C-polysaccharide antigen of which contains not more than 10% by weight of protein, and preferably less which has been purified with 0.1 N Na OH prior to deproteinizing. Also disclosed are polyvalent antibodies raised against which have been affinity purified by passing them over a chromatographic affinity matrix to which is coupled the purified and at least partially deproteinized antigen to render them antigen-specific.

Process And Materials For The Rapid Detection Of Streptococcus Pneumoniae Employing Purified Antigen-Specific Antibodies

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US Patent:
20070265433, Nov 15, 2007
Filed:
Apr 26, 2007
Appl. No.:
11/740738
Inventors:
Norman Moore - North Berwick ME, US
Mary Fent - Cumberland Center ME, US
Vladimir Koulchin - Portland ME, US
Elena Molokova - Portland ME, US
Assignee:
Binax, Inc. - Portland ME
International Classification:
C07K 16/00
C07H 3/00
US Classification:
530387900, 536123100
Abstract:
Disclosed is a cell wall C-polysaccharide antigen of which contains not more than 10% by weight of protein, and preferably less which has been purified with 0.1N Na OH prior to deproteinizing. Also disclosed are polyvalent antibodies raised against which have been affinity purified by passing them over a chromatographic affinity matrix to which is coupled the purified and at least partially deproteinized antigen to render them antigen-specific.

Method For Detecting The Presence Of Target Bacteria Or A Target Component Carbohydrate Antigen Thereof

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US Patent:
20080096236, Apr 24, 2008
Filed:
Jun 11, 2007
Appl. No.:
11/761255
Inventors:
Vladimir Koulchin - Portland ME, US
Norman Moore - North Berwick ME, US
Elena Molokova - Portland ME, US
Mary Fent - Cumberland Center ME, US
Assignee:
Binax, Inc. - Portland ME
International Classification:
G01N 33/569
C07K 16/12
C12P 19/00
US Classification:
435007320, 435072000, 530389500
Abstract:
A process is disclosed for separating a carbohydrate antigen from a Gram-positive or Gram-negative bacteria in a purified form that contains no more than 10% protein. The separated antigen is coupled to an affinity column, over which polyclonal antibodies to the same bacteria are chromatographed and recovered in a purified form that exhibits high specificity and sensitivity in immunoassays for the raw carbohydrate antigen corresponding to the purified antigen on the column. A particularly preferred form of rapid immunochromatographic assay employing the purified antibodies, which assay is very useful as an aid to rapid diagnosis of diseases caused by bacteria, is disclosed.

Process And Materials For The Rapid Detection Of Streptococcus Pneumoniae Employing Purified Antigen-Specific Antibodies

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US Patent:
20080241191, Oct 2, 2008
Filed:
Oct 31, 2007
Appl. No.:
11/982410
Inventors:
Norman James Moore - North Berwick ME, US
Mary Kathleen Fent - Cumberland Center ME, US
Vladimir Andrei Koulchin - Portland ME, US
Elena Valentin Molokova - Portland ME, US
Assignee:
Binax, Inc. - Portland ME
International Classification:
A61K 39/09
C07K 16/12
US Classification:
4242441, 5303895
Abstract:
Disclosed is a cell wall C-polysaccharide antigen of which contains not more than 10% by weight of protein, and preferably less which has been purified with 0.1N NaOH prior to deproteinizing. Also disclosed are polyvalent antibodies raised against which have been affinity purified by passing them over a chromatographic affinity matrix to which is coupled the purified and at least partially deproteinized antigen to render them antigen-specific.

Method For Detecting The Presence Of Target Bacteria Or A Target Component Carbohydrate Antigen Thereof

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US Patent:
20120135420, May 31, 2012
Filed:
Oct 31, 2007
Appl. No.:
11/982400
Inventors:
Vladimir Andrei Koulchin - Portland ME, US
Norman James Moore - North Berwick ME, US
Elena Valentin Molokova - Portland ME, US
Mary Kathleen Fent - Cumberland Center ME, US
Assignee:
Binax, Inc - Portland ME
International Classification:
G01N 33/569
C12P 19/04
G01N 33/53
C07K 1/22
C07K 16/12
US Classification:
435 71, 5303895, 436501, 435101
Abstract:
A process is disclosed for separating a carbohydrate antigen from a Gram-positive or Gram-negative bacteria in a purified form that contains no more than 10% protein. The separated antigen is coupled to an affinity column, over which polyclonal antibodies to the same bacteria are chromatographed and recovered in a purified form that exhibits high specificity and sensitivity in immunoassays for the raw carbohydrate antigen corresponding to the purified antigen on the column. A particularly preferred form of rapid immunochromatographic assay employing the purified antibodies, which assay is very useful as an aid to rapid diagnosis of diseases caused by bacteria, is disclosed.
Vladimir A Koulchin from Portland, ME, age ~71 Get Report