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Vladislav V Telyatnikov

from Lansdale, PA
Age ~46
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Also known as:
Vlad Telyatnikov, V Telyatnikov, Vladislav V
Connected to:
Boleslovas A Telycenas, 102Raisa P Telyeten, 33Alee W Telyfusi, 62Rebecca A Telzerow, 41Jose Tem, 64Melinda Tem, 34Jordan Tema, 46Jose Tema, 42Kerins Tema, 26Jeri L Temaat, 62

Vladislav Telyatnikov Phones & Addresses

  • Lansdale, PA
  • 2408 Lexington Ct, Norristown, PA 19403
  • Willow Grove, PA
  • 103 Upland Ave #14, Horsham, PA 19044
  • 434 Vine St, Hatfield, PA 19440
  • Detroit, MI
  • Philadelphia, PA

Industries

Pharmaceuticals

Resumes

Resumes

Vladislav Telyatnikov Photo 1

Synthetic Organic/Medicinal Chemist

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Location:
Greater Philadelphia Area
Industry:
Pharmaceuticals

Publications

Us Patents

Process For Reducing Contaminating Michael Acceptor Levels In Oxycodone And Other Compositions

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US Patent:
7875623, Jan 25, 2011
Filed:
Nov 22, 2006
Appl. No.:
11/603956
Inventors:
Jules A. Shafer - Gwynedd Valley PA, US
Vladislav V. Telyatnikov - Hatfield PA, US
Hao Wang - Singapore, SG
Assignee:
Controlled Chemicals, Inc. - Colmar PA
International Classification:
A61K 31/485
C07D 489/08
US Classification:
514282, 546 45
Abstract:
The present invention relates to processes for removal of Michael acceptors from certain compositions wherein the composition is treated with a thiol-containing compound under conditions sufficient to remove Michael acceptors and the resulting thiol-Michael adducts. Certain embodiments of the present invention enable quantification and/or removal of Michael acceptors and/or Michael acceptor precursors.

Compounds And Methods For Lowering The Abuse Potential And Extending The Duration Of Action Of A Drug

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US Patent:
20040204434, Oct 14, 2004
Filed:
Mar 15, 2004
Appl. No.:
10/800898
Inventors:
Jules Shafer - Gwynedd Valley PA, US
Vladislav Telyatnikov - Hatfield PA, US
Zhiwei Guo - Franklin Park NJ, US
Assignee:
Controlled Chemicals Inc.
International Classification:
A61K031/485
US Classification:
514/282000, 546/044000
Abstract:
The abuse potential of a bioavailable drug such as an opiate analgesic agent is reduced and its duration of action is extended by converting it to a poorly absorbed ester prodrug or other prodrug derivative prior to formulation. Unlike many existing sustained release formulations of active pharmaceutical agents wherein an active pharmaceutical agent can be released by chewing, crushing, or otherwise breaking tablets or capsule beads containing the active pharmaceutical agent, such mechanical processing of tablets or capsule beads containing a prodrug of this invention neither releases the active drug nor compromises the controlled conversion of prodrug to drug. Moreover, tablets and capsule beads containing prodrugs of this invention or other drugs can be formulated with a sufficient amount of a thickening agent such as hydroxypropylmethylcellulose or carboxymethylcellulose to impede inappropriate intravenous and nasal administration of formulations that are not indicated for these modes of administration.

Compounds And Methods For Lowering The Abuse Potential And Extending The Duration Of Action Of A Drug

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US Patent:
20070203165, Aug 30, 2007
Filed:
Apr 30, 2007
Appl. No.:
11/742566
Inventors:
Jules Shafer - Gwynedd Valley PA, US
Vladislav Telyatnikov - Hatfield PA, US
Zhiwei Guo - Franklin Park NJ, US
Assignee:
CONTROLLED CHEMICALS, INC. - Colmar PA
International Classification:
A61K 31/485
C07D 489/02
US Classification:
514282000, 546044000
Abstract:
The abuse potential of a bioavailable drug such as an opiate analgesic agent is reduced and its duration of action is extended by converting it to a poorly absorbed ester prodrug or other prodrug derivative prior to formulation. Unlike many existing sustained release formulations of active pharmaceutical agents wherein an active pharmaceutical agent can be released by chewing, crushing, or otherwise breaking tablets or capsule beads containing the active pharmaceutical agent, such mechanical processing of tablets or capsule beads containing a prodrug of this invention neither releases the active drug nor compromises the controlled conversion of prodrug to drug. Moreover, tablets and capsule beads containing prodrugs of this invention or other drugs can be formulated with a sufficient amount of a thickening agent such as hydroxypropylmethylcellulose or carboxymethylcellulose to impede inappropriate intravenous and nasal administration of formulations that are not indicated for these modes of administration.

Process For Reducing Contaminating Michael Acceptor Levels In Oxycodone And Other Compositions

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US Patent:
20110136849, Jun 9, 2011
Filed:
Dec 6, 2010
Appl. No.:
12/960991
Inventors:
Jules A. Shafer - Gwynedd Valley PA, US
Vladislav V. Telyatnikov - Hatfield PA, US
Hao Wang - Singapore, SG
International Classification:
A61K 31/4355
A61P 25/04
US Classification:
514282
Abstract:
The present invention relates to processes for removal of Michael acceptors from certain compositions wherein the composition is treated with a thiol-containing compound under conditions sufficient to remove Michael acceptors and the resulting thiol-Michael adducts. Certain embodiments of the present invention enable quantification and/or removal of Michael acceptors and/or Michael acceptor precursors.

Novel Cationic Lipids With Various Head Groups For Oligonucleotide Delivery

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US Patent:
20120149894, Jun 14, 2012
Filed:
Aug 18, 2010
Appl. No.:
13/390702
Inventors:
Mark Cameron - Brick NJ, US
Jennifer R. Davis - Richboro PA, US
Andrea R. Geiser - Lansdale PA, US
Matthew G. Stanton - Marlton NJ, US
Vladislav V. Telyatnikov - Willow Grove PA, US
Lu Tian - Jamison PA, US
Weimin Wang - Churchville PA, US
International Classification:
C07J 9/00
C07J 43/00
US Classification:
540113, 552544
Abstract:
The instant invention provides for novel cationic lipids that can be used in combination with other lipid components such as cholesterol and PEG-lipids to form lipid nanoparticles with siRNA, to facilitate the cellular uptake and endosomal escape, and to knockdown target mRNA both in vitro and in vivo.

Process For Reducing Contaminating Michael Acceptor Levels In Oxycodone And Other Compositions

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US Patent:
20170027199, Feb 2, 2017
Filed:
Aug 1, 2016
Appl. No.:
15/225699
Inventors:
- Colmar PA, US
Vladislav V. Telyatnikov - Hatfield PA, US
Hao Wang - Singapore, SG
Assignee:
Controlled Chemicals, Inc. - Colmar PA
International Classification:
A23L 5/20
G01N 30/74
G01N 33/15
C07D 489/08
G01N 33/02
Abstract:
The present invention relates to processes for removal of Michael acceptors from certain compositions wherein the composition is treated with a thiol-containing compound under conditions sufficient to remove Michael acceptors and the resulting thiol-Michael adducts. Certain embodiments of the present invention enable quantification and/or removal of Michael acceptors and/or Michael acceptor precursors.

Novel Catatonic Lipids With Various Head Groups For Oligonucleotide Delivery

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US Patent:
20160113874, Apr 28, 2016
Filed:
Oct 6, 2015
Appl. No.:
14/876402
Inventors:
- Cambridge MA, US
Jennifer R. DAVIS - Richboro PA, US
Andrea R. GEISER - Lansdale PA, US
Matthew G. STANTON - Marlton NJ, US
Vladislav V. TELYATNIKOV - Willow Grove PA, US
Lu TIAN - Jamison PA, US
Weimin WANG - Churchville PA, US
International Classification:
A61K 9/127
C07J 43/00
A61K 31/7088
C07J 41/00
Abstract:
The instant invention provides for novel cationic lipids that can be used in combination with other lipid components such as cholesterol and PEG-lipids to form lipid nanoparticles with siRNA, to facilitate the cellular uptake and endosomal escape, and to knockdown target mRNA both in vitro and in vivo.

Process For Reducing Contaminating Michael Acceptor Levels In Oxycodone And Other Compositions

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US Patent:
20150148537, May 28, 2015
Filed:
Dec 30, 2014
Appl. No.:
14/586239
Inventors:
- Colmar PA, US
Vladislav V. Telyatnikov - Hatfield PA, US
Hao Wang - Singapore, SG
Assignee:
Controlled Chemicals, Inc. - Colmar PA
International Classification:
C07D 489/08
US Classification:
546 45
Abstract:
The present invention relates to processes for removal of Michael acceptors from certain compositions wherein the composition is treated with a thiol-containing compound under conditions sufficient to remove Michael acceptors and the resulting thiol-Michael adducts. Certain embodiments of the present invention enable quantification and/or removal of Michael acceptors and/or Michael acceptor precursors.
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Vladislav V Telyatnikov from Lansdale, PA, age ~46 Get Report