Yu Chi Chen

6406861, Jun 18, 2002

Oct 6, 1999

09/413044

Daniel R. Henderson - Palo Alto CA
Yu Chen - Sunnyvale CA
De Chao Yu - Foster City CA

Cell Genesys, Inc. - Foster City CA

G01N 3353

435 71, 4241401, 4242331, 4241311, 4241591, 4242781, 424 931, 530351, 514885

Methods of reducing pre-existing humoral immunity to a viral immunogenic therapeutic agent such as adenovirus, using immunoapheresis are disclosed. Antibodies specific for the viral immunogenic therapeutic agent are selectively removed from the blood of an individual prior to administration of the viral immunogenic therapeutic agent by reaction extracorporeally with an immunosorbent which specifically binds the antibody. After the antibody is selectively removed from the blood, the blood is reinfused into the patient and the viral immunogenic therapeutic agent is administered. The invention also provides kits and compositions for selective removal of anti-viral antibody.

6884327, Apr 26, 2005

Mar 16, 2002

10/101492

Tao Pan - San Jose CA, US
Richard E. Demaray - Portola Valley CA, US
Yu Chen - San Jose CA, US
Yong Jin Xie - Cupertino CA, US
Rajiv Pethe - San Jose CA, US

C23C014/34

20419212, 4272481, 427259, 427282

A process for forming a mode size converter with an out-of-plane taper formed during deposition with a shadow mask is disclosed. Mode-size converters according to the present invention can have any number of configurations. Measured coupling efficiencies for waveguides with mode size converters according to the present invention show marked improvement.

6911200, Jun 28, 2005

Mar 21, 2001

09/814357

Yu Chen - Cupertino CA, US
Daniel R. Henderson - Palo Alto CA, US

Cell Genesys, Inc. - Foster City CA

A01N063/00
A61K048/00
C12N015/861

424 932, 435455, 435456, 4353201

The invention provides methods of treating neoplasia using combinations of target cell-specific replication competent adenoviral vectors and chemotherapy, radiation therapy or combinations thereof. The adenoviral vectors are target cell-specific for the particular type of neoplasia for which treatment is necessary and the combination with the chemotherapy and/or radiation leads to synergistic treatment over existing adenoviral therapy or traditional chemotherapy and radiation therapy.

7276233, Oct 2, 2007

Jun 27, 2005

11/166234

Yu Chen - Cupertino CA, US
Daniel R. Henderson - Palo Alto CA, US

Cell Genesys, Inc. - South San Francisco CA

A01N 63/00
A61K 48/00

424 932

The invention provides methods of treating neoplasia using combinations of target cell-specific replication competent adenoviral vectors and chemotherapy, radiation therapy or combinations thereof. The adenoviral vectors are target cell-specific for the particular type of neoplasia for which treatment is necessary and the combination with the chemotherapy and/or radiation leads to synergistic treatment over existing adenoviral therapy or traditional chemotherapy and radiation therapy.

7673143, Mar 2, 2010

Feb 24, 2004

10/786345

William J. Yeager - Menlo Park CA, US
Yu Chen - San Jose CA, US
Brian K. Raymor - Arlington VA, US
Jackson Wong - Menlo Park CA, US

Sun Microsystems, Inc. - Menlo Park CA

H04L 9/32

713175, 713153, 713168

A method for securing a communication between a peer node and an intermediary peer node in a peer-to-peer network comprises the peer node generating a secured communication request to the intermediary peer node. The intermediary peer node authenticates the peer node in response to the secured communication request. The intermediary peer node issues a signed certificate of authority upon successful authentication.

7977240, Jul 12, 2011

Feb 13, 2009

12/371239

Joerg Rockenberger - San Jose CA, US
Yu Chen - Pearland TX, US
Fabio Zürcher - Brisbane CA, US
Scott Haubrich - Albuquerque NM, US

Kovio, Inc. - Milpitas CA

H01L 21/44
H01L 21/4763

438674, 438622, 438637, 257E21273

Metal ink compositions, methods of forming such compositions, and methods of forming conductive layers are disclosed. The ink composition includes a bulk metal, a transition metal source, and an organic solvent. The transition metal source may be a transition metal capable of forming a silicide, in an amount providing from 0. 01 to 50 at. % of the transition metal relative to the bulk metal. Conductive structures may be made using such ink compositions by forming a silicon-containing layer on a substrate, printing a metal ink composition on the silicon-containing layer, and curing the composition. The metal inks of the present invention have high conductivity and form low resistivity contacts with silicon, and reduce the number of inks and printing steps needed to fabricate integrated circuits.

8386304, Feb 26, 2013

May 29, 2008

12/129593

Yu Chen - Irvine CA, US
Ramin Rahbari - Tustin CA, US

G06Q 40/00

705 14, 705 26, 705 27, 725 46, 725 47, 725 39

A environment of server and client systems for revenue generation, where a component is provided for broadcasters to broadcast and/or transmit programming, and where advertisers can create advertisement, and bid for advertising time on the transmitted programming. Advertisers are empowered by the network's ability to perform targeted advertising and/or product placement base on viewer attribute, programming content, and other criteria collected by the environment. Broadcasters are empowered by the network's ability to produce relatively high conversion rate using an viewer interface allowing enabling viewers to perform click-to-buy, click-to-send-lead, and/or click-to-send information, without much disruption to viewing of the transmitted programming. Also disclosed is a business method of generating revenue by utilizing an environment of server and client systems for targeted advertising and/or product placement, where incentives are created by and for broadcasters, advertisers, content providers, creator of the environment, and viewers.

8495085, Jul 23, 2013

Sep 27, 2010

12/891146

Mengchu Cai - San Jose CA, US
Yu Chen - San Jose CA, US
Eric Naoto Katayama - San Jose CA, US

International Business Machines Corporation - Armonk NY

G06F 17/30

707769, 707770

Methods and apparatus, including computer program products, implementing and using techniques for performing a partial update of a hierarchically structured document referencing one or more records stored in a database. An expression specifying one or more updates to be applied to the document is received. The document is searched to find update target position(s). Based on the received expression, a pending update list is built. When an update target position is found, a row of a document column in a base table is updated with the new version number for the document. New database records for insertion into the new document version are generated from the pending update list. Old database records to be replaced are identified. A database table for the document is updated to mark the old database records as obsolete and to add new database records to be referenced in the new version of the document.